Anti-ABCA1 Monoclonal Antibody from EMD MILLIPORE
| Antigenic Specificity |
ABCA1 |
| Clone |
AB.H10 |
| Host Species |
Mouse |
| Reactive Species |
chicken, human, mouse |
| Isotype |
IgG1 |
| Format |
purified |
| Size |
100 µg |
| Applications |
ELISA;Immunoprecipitation;Western Blotting;Immunohistochemistry (Paraffin) |
| Description |
Mutations in the ABCA1 gene are associated with Tangier disease (TD). TD is an autosomal recessive disorder results from an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI. |
| Catalog # |
MAB10005 |
| Price |
please inquire |
| Other Names |
ATP-binding cassette transporter 1; ABC-1; Cholesterol efflux regulatory protein |
| Supplier Data Page |
Anti-ABCA1 from EMD MILLIPORE |
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