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Anti-14-3-3 Polyclonal Antibody from NOVUS BIOLOGICALS, LLC
Anti-14-3-3 Polyclonal Antibody from NOVUS BIOLOGICALS, LLC
| Antigenic Specificity |
14-3-3 |
| Clone |
polyclonal |
| Host Species |
Rabbit |
| Reactive Species |
human, mouse and rat. |
| Isotype |
IgG |
| Format |
immunogen affinity purified |
| Size |
1.0ml, 0.2 mg/ml |
| Applications |
This antibody is useful for Immunohistochemistry, Immunoprecipitation and Western Blot. |
| Description |
Specificity: Broadly reactive among the 14-3-3 family. This recognizes alpha, beta, zeta (delta) and theta 14-3-3. Immunogen: Synthetic peptide mapping to the amino terminal domain of human 14-3-3. 14-3-3 family of proteins is composed of seven isotypes, beta, gamma, zeta, epsilon, tau, eta, and sigma, that play critical roles in cell signaling events that control cell cycle progression, transcriptional alterations, and apoptosis (1-4). 14-3-3 proteins were the first signaling molecules to be identified as specific phosphoserine/threonine binding proteins (1). 14-3-3 can serve as a direct regulator of its target by altering the function of the protein (3). 14-3-3 protein targets include the signalling intermediates Raf, MEKK, PI-3 kinase and IRS-1, cell cycle proteins CDK2, Wee1, and Cdc25, and apoptosis proteins BAD and ASK-1 (3,4). |
| Catalog # |
NB100-2140 |
| Price |
$325 |
| Other Names |
YWHAQ |
| Supplier Data Page |
Anti-14-3-3 from NOVUS BIOLOGICALS, LLC |
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Directory disclaims responsibility for its accuracy. Pricing is supplier's
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