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Anti-AATF Polyclonal Antibody from NOVUS BIOLOGICALS, LLC
Anti-AATF Polyclonal Antibody from NOVUS BIOLOGICALS, LLC
| Antigenic Specificity |
AATF |
| Clone |
polyclonal |
| Host Species |
Rabbit |
| Reactive Species |
human,mouse,rat |
| Isotype |
IgG |
| Format |
immunogen affinity purified |
| Size |
0.1mg, 1 mg/ml |
| Applications |
This product is useful for Western Blot ELISA. |
| Description |
Specificity: AATF Antibody detects endogenous levels of total AATF protein. Immunogen: The antiserum was produced against synthesized peptide derived from human AATF. The immunogen region is: N-terminal. AATF (Apoptosis-antagonizing transcription factor), also termed Che-1, was identified as interacting protein of Dlk/ZIP kinase and RNA polymerase II. AATF has additionally been shown to bind Rb, thereby activating transcription factor E2F and promoting cell cycle progression. AATF enhances steroid receptor-mediated transactivation in a hormone and dose-dependent manner. It is involved in the activation of anti-apoptotic pathways. AATF contains an extremely acidic domain, a putative leucine zipper and a nuclear localization signal, features which are characteristic of transcription factors. Recently AATF has been shown to protect neural cells against oxidative damage suggesting it may have therapeutic uses in Alzheimer's Disease. |
| Catalog # |
NBP1-68164-0.1mg |
| Price |
$295.00 |
| Other Names |
AATF. SwissProt ID: Q9NY61 |
| Supplier Data Page |
Anti-AATF from NOVUS BIOLOGICALS, LLC |
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