| Antigenic Specificity |
ABCB8 |
| Clone |
polyclonal |
| Host Species |
Rabbit |
| Reactive Species |
human,mouse. computational sequence homology: mouse:100%; human:100%; giant panda:92%; dog:92%; sumatran orangutan:92%; rat:92%; black-legged tick:84%; leptotrichia goodfellowii f0264:78%; gordonibacter pamelaeae 7-10-1-b:76%; |
| Isotype |
n/a |
| Format |
peptide affinity purified |
| Size |
50ug |
| Applications |
This is a rabbit polyclonal antibody against ABCB8 and was validated on Western blot. |
| Description |
Immunogen: Synthetic peptides corresponding to ABCB8(ATP-binding cassette, sub-family B (MDR/TAP), member 8) The peptide sequence was selected form the middle region of ABCB8. Immunogenizing peptide sequence EPVLFGTTIMENIRFGKLEASDEEVYTAAREANAHEFITSFPEGYNTVVG. This product comes as a Lyophilized powder. Reconstitution Instructions: Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. The membrane-associated protein ABCB8 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCB8 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes. |
| Catalog # |
NBP1-59553 |
| Price |
$325.00 |
| Other Names |
EST328128, MABC1, M-ABC1. SwissProt ID: Q9NUT2 |
| Supplier Data Page |
Anti-ABCB8 from NOVUS BIOLOGICALS, LLC |
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