| Antigenic Specificity |
ABCG1 |
| Clone |
polyclonal |
| Host Species |
Rabbit |
| Reactive Species |
mouse and human protein. there is 100%/100% identity/homology of the immunogen used for this production and the human protein sequence. there is 84%/89% for mouse and 78%/88% for rat. |
| Isotype |
n/a |
| Format |
Peptide affinity purified |
| Size |
0.1ml, 1.0 mg/ml |
| Applications |
This antibody is useful for Western blot on mouse peritoneal macrophages treated with 22-R-hydroxycholesterol and T0901317 (stimulating ABCG1 expression) and immunohistochemistry. The theoretical molecular weight of ABCG1 is ~75.6 kDa, as seen by Western |
| Description |
The specificity of this is for ABCG1. Immunogen: A synthetic peptide made to an internal region of human ABCG1 (between residues 300-400). ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. The ABC transporter ABCG1 (ABC8) is expressed on the cell surface and in intracellular compartments of cholesterol-laden macrophages and is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. In contrast, lipid efflux in cholesterol-laden macrophages, mediated by the cholesterol acceptor HDL(3), suppresses the expression of ABCG1. |
| Catalog # |
NB400-132 |
| Price |
$295 |
| Other Names |
ABC8 , ABC transporter 8 , ATP-binding cassette , ATP-binding cassette sub-family G member 1 an, ATP-binding cassette transporter 8 , ATP-binding cassette transporter member 1 of , homolog |
| Supplier Data Page |
Anti-ABCG1 from NOVUS BIOLOGICALS, LLC |
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