| Antigenic Specificity |
ABCG8 |
| Clone |
polyclonal |
| Host Species |
Rabbit |
| Reactive Species |
human and mouse. |
| Isotype |
n/a |
| Format |
peptide affinity purified |
| Size |
0.05ml, 1.0 mg/ml |
| Applications |
This antibody is useful for Western Blot where a doublet is seen at ~67kDa and ~72kDa. Longer exposure times are needed to visualize the wild type ABCG8. For mouse, 100 ug protein (B6/129AKRFVB liver homogenate) loaded with antibody diluted at 1:500. |
| Description |
Specificity: NB400-117 is specific for human ABCG8. Immunogen: A synthetic peptide from the n-terminal region of human ABCG8 protein. ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. ABCG8, expressed at high levels in the liver and intestine, normally cooperates with ABCG5 to limit intestinal absorption and promote biliary excretion of sterols. The mutated form of this transporter can lead to sterol accumulation and atherosclerosis or sitosterolemia, a rare autosomal recessive disorder, characterized by hyperabsorption of sterols and the inability to excrete sterols into bile. |
| Catalog # |
NB400-117SS |
| Price |
$125.00 |
| Other Names |
ATP binding cassette G8, ATP binding cassette sub family G (WHITE) mem, ATP binding cassette sub family G member 8 an, GBD4, MGC142217, Sterolin 2, STSL. SwissProt ID: Q9H221 |
| Supplier Data Page |
Anti-ABCG8 from NOVUS BIOLOGICALS, LLC |
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Directory disclaims responsibility for its accuracy. Pricing is supplier's
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