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Anti-Abeta 42 Polyclonal Antibody from NOVUS BIOLOGICALS, LLC
Anti-Abeta 42 Polyclonal Antibody from NOVUS BIOLOGICALS, LLC
| Antigenic Specificity |
Abeta 42 |
| Clone |
polyclonal |
| Host Species |
Rabbit |
| Reactive Species |
n/a |
| Isotype |
n/a |
| Format |
peptide affinity purified |
| Size |
0.1mg |
| Applications |
The antibody specificity was assayed by dot blot analysis with the synthetic Amyloid (1-40) peptide antigen and Western blot analysis. The antibody titer is more than 10K for Dot blot and 1,000X for Western blot analysis (data not shown). It has not been tested in the other applications. However, for the first testing, we recommend 1/5,000 dilution for ELISA, 1/1,000 dilution for Western blot analysis (WB) of recombinant protein, 1/400 dilution for tissue extracts or cell lysates, 1/100 dilution for immunohistochemistry (IHC) staining on frozen cryosections, 1/50 dilution for IHC staining on paraffin embedded sections. |
| Description |
Specificity: Amyloid beta (37-42). Immunogen: This polyclonal antibody was raised by immunizing rabbit with a synthetic peptide containing 1-40 amino acids of amyloid. The amyloid beta peptide (A beta) is the main component of amyloid deposits found in the brain of patients afflicted with Alzheimer's disease. Brain to blood transport is believed to be a major determinant of the amount of amyloid beta protein (AbetaP) found in brain. Chronic brain hypoperfusion (CBH) initiates spatial memory loss in aging rats thus mimicking human mild cognitive impairment (MCI) and also increases A beta in the hippocampus. The memory and amyloid changes are preceded by NO upregulation in the hippocampus. These preliminary findings may be important in understanding, at least in part, the molecular mechanisms that precede memory impairment during chronic brain ischemia and as such, the pre-clinical stage leading to Alzheimer's disease. |
| Catalog # |
NBP1-05001 |
| Price |
$295.00 |
| Other Names |
ABPP, ABETA, A4, AAA, Alzheimer and 039;s disease amyloid protein , Alzheimer disease 1, Adap, Amyloid Beta A4 Precursor Protein, Amyloid of aging and alzheimer disease antibo, AD 1, AD1, APP, APPI, Appican, Beta Amyloid, Beta amyloid protein 40, Beta APP40, BetaAPP, Cerebral vascular amyloid peptide, CTFgamma, CVAP, Peptidase nexin II, PREA4, PN 2, PN II, PN2, Protease nexin II, APP |
| Supplier Data Page |
Anti-Abeta 42 from NOVUS BIOLOGICALS, LLC |
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