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Anti-TOB1, NT (Protein Tob1, Transducer of erbB-2 1, TROB1, TOB), Human Polyclonal Antibody from UNITED STATES BIOLOGICAL
Anti-TOB1, NT (Protein Tob1, Transducer of erbB-2 1, TROB1, TOB), Human Polyclonal Antibody from UNITED STATES BIOLOGICAL
| Antigenic Specificity |
TOB1, NT (Protein Tob1, Transducer of erbB-2 1, TROB1, TOB), Human |
| Clone |
polyclonal |
| Host Species |
Rabbit |
| Reactive Species |
human, mouse |
| Isotype |
IgG |
| Format |
purified by immunoaffinity chromatography. |
| Size |
100ug |
| Applications |
ELISA WB |
| Description |
TOB1 is a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90kD ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution:ELISA: 1:1,000Western Blot: 1:100-1:500Optimal dilutions to be determined by the researcher.Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
| Catalog # |
T7948-10 |
| Price |
please inquire |
| Other Names |
n/a |
| Supplier Data Page |
Anti-TOB1, NT (Protein Tob1, Transducer of erbB-2 1, TROB1, TOB), Human from UNITED STATES BIOLOGICAL |
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