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Anti-TOB2 (Protein Tob2, Transducer of erbB-2 2, Protein Tob4, KIAA1663, TOB4, TOBL, TROB2), Human Polyclonal Antibody from UNITED STATES BIOLOGICAL
Anti-TOB2 (Protein Tob2, Transducer of erbB-2 2, Protein Tob4, KIAA1663, TOB4, TOBL, TROB2), Human Polyclonal Antibody from UNITED STATES BIOLOGICAL
| Antigenic Specificity |
TOB2 (Protein Tob2, Transducer of erbB-2 2, Protein Tob4, KIAA1663, TOB4, TOBL, TROB2), Human |
| Clone |
polyclonal |
| Host Species |
Rabbit |
| Reactive Species |
bovine, dog, chicken, horse, human, mouse |
| Isotype |
IgG |
| Format |
purified by Protein A affinity chromatography. |
| Size |
100ug |
| Applications |
WB |
| Description |
TOB2 is a 344aa rich novel member of the Tob:BTG1 anti-proliferative family of proteins characterized by similarities in their N-terminal BTG:Tob homology domains. This anti-proliferative protein inhibits cell cycle progression from the G0:G1 to S phases and is involved in cell cycle regulation through interaction with Caf1, a component of the CCR4 transcription factor complex that associates with cyclin-dependent kinases. Recent reports suggest that TOB2 plays important roles in spermatogenesis, embryonic dorsoventral patterning, osteogenesis, T-cell activation, learning and memory and acts primarily as a transcriptional repressor in several signaling pathways. TOB2, a signaling protein, may participate in transcriptional regulation of several genes. It is a regulatory protein ubiquitously expressed in most of the tissues. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution:Western Blot: 0.5-1ug/mlOptimal dilutions to be determined by the researcher.Positive Control: Human heart lysateStorage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
| Catalog # |
T7948-20 |
| Price |
please inquire |
| Other Names |
Transducer of ERBB2, 2 |
| Supplier Data Page |
Anti-TOB2 (Protein Tob2, Transducer of erbB-2 2, Protein Tob4, KIAA1663, TOB4, TOBL, TROB2), Human from UNITED STATES BIOLOGICAL |
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