| TO |
n/a |
n/a |
n/a |
HARLAN |
More Info
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| prod |
n/a |
n/a |
n/a |
n/a |
More Info
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| AS 101 |
Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1alpha, IL-2 and TNF-alpha release. Purity > 98% |
50mg |
2446 |
TOCRIS BIOSCIENCE |
More Info
|
| AS 101 |
Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1alpha, IL-2 and TNF-alpha release. Purity > 98% |
10mg |
2446 |
TOCRIS BIOSCIENCE |
More Info
|
| AS 19 |
Reported potent 5-HT7 receptor agonist (IC50 = 0.83 nM). In vivo, enhances memory consolidation and reverses scopolamine- or dizocilpine-induced amnesia. Purity > 98% |
10mg |
1968 |
TOCRIS BIOSCIENCE |
More Info
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| AS 19 |
Reported potent 5-HT7 receptor agonist (IC50 = 0.83 nM). In vivo, enhances memory consolidation and reverses scopolamine- or dizocilpine-induced amnesia. Purity > 98% |
50mg |
1968 |
TOCRIS BIOSCIENCE |
More Info
|
| 293 |
n/a |
n/a |
n/a |
NIH AIDS RESEARCH & REAGENTS |
More Info
|
| 293 |
n/a |
n/a |
n/a |
VIRCELL S.L. |
More Info
|
| AS 605240 |
Potent and selective inhibitor of PI 3-kinase gamma (PI3Kgamma) (IC50 = 8 nM). Displays 30-fold selectivity over PI3Kdelta and PI3Kbeta and 7.5-fold selectivity over PI3Kalpha. Suppresses the progression of joint inflammation and damage in both ly... |
10mg |
3578 |
TOCRIS BIOSCIENCE |
More Info
|
| AS 605240 |
Potent and selective inhibitor of PI 3-kinase gamma (PI3Kgamma) (IC50 = 8 nM). Displays 30-fold selectivity over PI3Kdelta and PI3Kbeta and 7.5-fold selectivity over PI3Kalpha. Suppresses the progression of joint inflammation and damage in both ly... |
50mg |
3578 |
TOCRIS BIOSCIENCE |
More Info
|
| 92.1.7 |
n/a |
n/a |
n/a |
VIRCELL S.L. |
More Info
|
| A2.01 |
n/a |
n/a |
n/a |
NIH AIDS RESEARCH & REAGENTS |
More Info
|
| A3.01 |
n/a |
n/a |
n/a |
NIH AIDS RESEARCH & REAGENTS |
More Info
|
| A549 |
n/a |
n/a |
n/a |
VIRCELL S.L. |
More Info
|
| A-779 |
Purity: > 95% |
1 mg |
06-271-83027 |
GENWAY BIOTECH INC. |
More Info
|
| A 769662 |
AMP-activated protein kinase activator |
10mg |
Asc-335-10mg |
ASCENT SCIENTIFIC LTD. |
More Info
|
| A 769662 |
AMP-activated protein kinase activator |
50mg |
Asc-335-50mg |
ASCENT SCIENTIFIC LTD. |
More Info
|
| A 803467 |
Selective NaV1.8 channel blocker |
10mg |
Asc-282-10mg |
ASCENT SCIENTIFIC LTD. |
More Info
|
| A 803467 |
Selective NaV1.8 channel blocker |
50mg |
Asc-282-50mg |
ASCENT SCIENTIFIC LTD. |
More Info
|
| A23187 |
Ca2+ ionophore |
10mg |
Asc-287-10mg |
ASCENT SCIENTIFIC LTD. |
More Info
|
| A23187 |
Ca2+ ionophore |
50mg |
Asc-287-50mg |
ASCENT SCIENTIFIC LTD. |
More Info
|
| A 205804 |
Selective inhibitor of E-selectin and ICAM-1 expression (IC50 values are 20, 25 and > 1000 nM for TNF-alpha-induced E-selectin, ICAM-1 and VCAM-1 expression respectively). Effective inhibitor of cell-cell adhesion in an in vitro flow experiment. P... |
10mg |
2524 |
TOCRIS BIOSCIENCE |
More Info
|
| A 205804 |
Selective inhibitor of E-selectin and ICAM-1 expression (IC50 values are 20, 25 and > 1000 nM for TNF-alpha-induced E-selectin, ICAM-1 and VCAM-1 expression respectively). Effective inhibitor of cell-cell adhesion in an in vitro flow experiment. P... |
50mg |
2524 |
TOCRIS BIOSCIENCE |
More Info
|
| A 740003 |
Potent, selective and competitive P2X7 receptor antagonist (IC50 values are 18 and 40 nM for rat and human receptors respectively). Displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100 µM. Reduces nocicep... |
10mg |
3701 |
TOCRIS BIOSCIENCE |
More Info
|
| A 740003 |
Potent, selective and competitive P2X7 receptor antagonist (IC50 values are 18 and 40 nM for rat and human receptors respectively). Displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100 µM. Reduces nocicep... |
50mg |
3701 |
TOCRIS BIOSCIENCE |
More Info
|
| A 769662 |
Potent, reversible AMP-activated protein kinase (AMPK) activator (EC50 = 0.8 µM) that displays selectivity towards beta1 subunit-containing heterotrimers. Inhibits fatty acid synthesis (IC50 = 3.2 µM) and decreases plasma glucose and t... |
10mg |
3336 |
TOCRIS BIOSCIENCE |
More Info
|
| A 769662 |
Potent, reversible AMP-activated protein kinase (AMPK) activator (EC50 = 0.8 µM) that displays selectivity towards beta1 subunit-containing heterotrimers. Inhibits fatty acid synthesis (IC50 = 3.2 µM) and decreases plasma glucose and t... |
50mg |
3336 |
TOCRIS BIOSCIENCE |
More Info
|
| A 803467 |
Selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively). Shows no significant activity against TRPV1, P2X2/3, CaV2.2 and KCNQ2/3 channels. Anti... |
10mg |
2976 |
TOCRIS BIOSCIENCE |
More Info
|
| A 803467 |
Selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively). Shows no significant activity against TRPV1, P2X2/3, CaV2.2 and KCNQ2/3 channels. Anti... |
50mg |
2976 |
TOCRIS BIOSCIENCE |
More Info
|
| A 83-01 |
Selective inhibitor of TGF-beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-beta-induced epitheli... |
10mg |
2939 |
TOCRIS BIOSCIENCE |
More Info
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| A 83-01 |
Selective inhibitor of TGF-beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-beta-induced epitheli... |
50mg |
2939 |
TOCRIS BIOSCIENCE |
More Info
|
| A 841720 |
Potent, non-competitive mGlu1 receptor antagonist that displays 34-fold selectivity over mGlu5 (IC50 values are 10 and 342 nM respectively). Displays no significant activity at a range of other GPCRs, ion channels and transporters. Exhibits analge... |
10mg |
3060 |
TOCRIS BIOSCIENCE |
More Info
|
| A 841720 |
Potent, non-competitive mGlu1 receptor antagonist that displays 34-fold selectivity over mGlu5 (IC50 values are 10 and 342 nM respectively). Displays no significant activity at a range of other GPCRs, ion channels and transporters. Exhibits analge... |
50mg |
3060 |
TOCRIS BIOSCIENCE |
More Info
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| A 922500 |
Diacylglycerol acyltransferase 1 (DGAT-1) inhibitor (IC50 values are 7 and 24 nM at human and mouse DGAT-1 respectively) that is devoid of activity at DGAT-2, ACAT1 or ACAT2. Induces significant weight loss without altering food intake, and decrea... |
10mg |
3587 |
TOCRIS BIOSCIENCE |
More Info
|
| A 987306 |
Potent histamine H4 receptor antagonist (pKi values are 8.24 and 8.47 in human and rat H4 receptors respectively). Displays 162-fold, 620-fold, and > 1600-fold selectivity over human H3, H1 and H2 receptors. Blocks zymosan-induced neutrophil reflu... |
10mg |
3640 |
TOCRIS BIOSCIENCE |
More Info
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| A 987306 |
Potent histamine H4 receptor antagonist (pKi values are 8.24 and 8.47 in human and rat H4 receptors respectively). Displays 162-fold, 620-fold, and > 1600-fold selectivity over human H3, H1 and H2 receptors. Blocks zymosan-induced neutrophil reflu... |
50mg |
3640 |
TOCRIS BIOSCIENCE |
More Info
|
| A-71623 |
Potent CCK1 agonist (IC50 = 3.7 nM) with 1200-fold selectivity over the CCK2 receptor. Suppresses food intake following central or peripheral administration. Purity > 98% |
1mg |
2411 |
TOCRIS BIOSCIENCE |
More Info
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| A77 1726 |
Leflunomide metabolite that blocks TNF-dependent NF-κB activation and gene expression. Inhibits the activity of dihydroorotate dehydrogenase (DHO-DH; IC50 = 220 nM). Reported to reduce IFN-γ-induced expression of iNOS in L929 fibroblas... |
n/a |
100128 |
CALBIOCHEM/EMD BIOSCIENCES |
More Info
|
| AA2 |
n/a |
n/a |
n/a |
NIH AIDS RESEARCH & REAGENTS |
More Info
|
| AA 2414 |
Thromboxane A2 (TP) receptor antagonist. Antiasthmatic agent; inhibits platelet aggregation and bronchoconstriction induced by a TXA2 mimetic in guinea pigs. Purity > 98% |
50mg |
3025 |
TOCRIS BIOSCIENCE |
More Info
|
| AA 2414 |
Thromboxane A2 (TP) receptor antagonist. Antiasthmatic agent; inhibits platelet aggregation and bronchoconstriction induced by a TXA2 mimetic in guinea pigs. Purity > 98% |
10mg |
3025 |
TOCRIS BIOSCIENCE |
More Info
|
| AACOCF3 |
Inhibitor of cytosolic (85 kDa) phospholipase A2. Also inhibits fatty acid amide hydrolase (FAAH, anandamide amidase) in vitro. Purity > 98% |
25mg |
1462 |
TOCRIS BIOSCIENCE |
More Info
|
| AACOCF3 |
Inhibitor of cytosolic (85 kDa) phospholipase A2. Also inhibits fatty acid amide hydrolase (FAAH, anandamide amidase) in vitro. Purity > 98% |
5mg |
1462 |
TOCRIS BIOSCIENCE |
More Info
|
| AACOCF3 |
A cell-permeable trifluoromethyl ketone analog of arachidonic acid. Potent and selective slow-binding inhibitor of cytosolic (85 kDa) phospholipase A2 (cPLA2; IC50 = ~20 µM). Specific inhibition of cPLA2 activity by AACOCF3 partially inhibit... |
n/a |
100109 |
CALBIOCHEM/EMD BIOSCIENCES |
More Info
|
| 17-AAG |
Inhibitor of heat shock protein 90 (Hsp90) chaperone activity, and an analog of geldanamycin (Cat. No. 1368). Subsequently inhibits the activity of oncogenic proteins such as p185erbB-2 (IC50 = 31 nM), N-ras, Ki-ras and c-Akt. Antitumor in vivo. P... |
1mg |
1515 |
TOCRIS BIOSCIENCE |
More Info
|
| 17-AAG |
A less toxic, potent, synthetic derivative of the ansamycin benzoquinone antibiotic Geldanamycin, Streptomyces hygroscopicus (Cat. No. 345805) that binds to Hsp90 (EC50 = 7.2 µM) and regulates its function. Induces apoptosis and displays ant... |
n/a |
100068 |
CALBIOCHEM/EMD BIOSCIENCES |
More Info
|
| AAPH |
A heat-sensitive, water-soluble, free radical initiator that induces oxidative stress by causing cellular damage associated with lipid peroxidation, protein modification, hemoglobin oxidation, and DNA strand breakage. Reported to induce apoptosis ... |
n/a |
100110 |
CALBIOCHEM/EMD BIOSCIENCES |
More Info
|
| ABS 205 |
Orally active valproic acid (Cat No. 2815) derivative that exhibits teratogenic and neuroprotective activity. Upregulates neural cell adhesion molecule (NCAM) expression, activates PPARdelta (IC50 = 0.6 mM) and increases Hoxa1 expression in rat em... |
50mg |
2721 |
TOCRIS BIOSCIENCE |
More Info
|
| ABS 205 |
Orally active valproic acid (Cat No. 2815) derivative that exhibits teratogenic and neuroprotective activity. Upregulates neural cell adhesion molecule (NCAM) expression, activates PPARdelta (IC50 = 0.6 mM) and increases Hoxa1 expression in rat em... |
10mg |
2721 |
TOCRIS BIOSCIENCE |
More Info
|
| ABTS |
2 g; 2,2'-Azino-di-[3-ethylben zthiazoline sulfonate (6)] diammonium salt, crystals. Formula: C18H16N4O6S4-(NH4)2Molecu lar weight: ABTS: Mr = 514.6, ABTS-(NH4)2: Mr = 548.7Solubility: soluble in water (c = 50 mg/ml)Note: The green color is due to f... |
n/a |
10102946001 |
ROCHE APPLIED SCIENCE |
More Info
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