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Name Description Size Catalog # Supplier  
TO n/a n/a n/a HARLAN More Info
prod n/a n/a n/a n/a More Info
AS 101 Purity: > 98%. Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1alpha, IL-2 and TNFalpha release. 50mg 2446 TOCRIS BIOSCIENCE More Info
AS 101 Purity: > 98%. Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1alpha, IL-2 and TNFalpha release. 10mg 2446 TOCRIS BIOSCIENCE More Info
AS 19 Purity: > 98%. Reported potent 5-HT7 receptor agonist (IC50 = 0.83 nM). In vivo, enhances memory consolidation and reverses scopolamine- or dizocilpine-induced amnesia. 10mg 1968 TOCRIS BIOSCIENCE More Info
AS 19 Purity: > 98%. Reported potent 5-HT7 receptor agonist (IC50 = 0.83 nM). In vivo, enhances memory consolidation and reverses scopolamine- or dizocilpine-induced amnesia. 50mg 1968 TOCRIS BIOSCIENCE More Info
293 n/a n/a n/a NIH AIDS RESEARCH & REAGENTS More Info
293 n/a n/a n/a VIRCELL S.L. More Info
92.1.7 n/a n/a n/a VIRCELL S.L. More Info
A2.01 n/a n/a n/a NIH AIDS RESEARCH & REAGENTS More Info
A3.01 n/a n/a n/a NIH AIDS RESEARCH & REAGENTS More Info
A549 n/a n/a n/a VIRCELL S.L. More Info
A 205804 Purity: > 98%. Selective inhibitor of E-selectin and ICAM-1 expression (IC50 values are 20, 25 and > 1000 nM for TNF-alpha-induced E-selectin, ICAM-1 and VCAM-1 expression respectively). Effective inhibitor of cell-cell adhesion in an in vitro flo... 50mg 2524 TOCRIS BIOSCIENCE More Info
A 205804 Purity: > 98%. Selective inhibitor of E-selectin and ICAM-1 expression (IC50 values are 20, 25 and > 1000 nM for TNF-alpha-induced E-selectin, ICAM-1 and VCAM-1 expression respectively). Effective inhibitor of cell-cell adhesion in an in vitro flo... 10mg 2524 TOCRIS BIOSCIENCE More Info
A 769662 Purity: > 98%. Potent, reversible AMP-activated protein kinase (AMPK) activator (EC50 = 0.8 µM) that displays selectivity towards beta1 subunit-containing heterotrimers. Inhibits fatty acid synthesis (IC50 = 3.2 µM) and decreases plasm... 50mg 3336 TOCRIS BIOSCIENCE More Info
A 769662 Purity: > 98%. Potent, reversible AMP-activated protein kinase (AMPK) activator (EC50 = 0.8 µM) that displays selectivity towards beta1 subunit-containing heterotrimers. Inhibits fatty acid synthesis (IC50 = 3.2 µM) and decreases plasm... 10mg 3336 TOCRIS BIOSCIENCE More Info
A 803467 Purity: > 98%. Selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively). Shows no significant activity against TRPV1, P2X2/3, CaV2.2 and KCNQ2/3... 10mg 2976 TOCRIS BIOSCIENCE More Info
A 803467 Purity: > 98%. Selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively). Shows no significant activity against TRPV1, P2X2/3, CaV2.2 and KCNQ2/3... 50mg 2976 TOCRIS BIOSCIENCE More Info
A 83-01 Purity: > 98%. Selective inhibitor of TGF-beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-beta-i... 10mg 2939 TOCRIS BIOSCIENCE More Info
A 83-01 Purity: > 98%. Selective inhibitor of TGF-beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-beta-i... 50mg 2939 TOCRIS BIOSCIENCE More Info
A 841720 Purity: > 98%. Potent, non-competitive mGlu1 receptor antagonist that displays 34-fold selectivity over mGlu5 (IC50 values are 10 and 342 nM respectively). Displays no significant activity at a range of other GPCRs, ion channels and transporters. ... 50mg 3060 TOCRIS BIOSCIENCE More Info
A 841720 Purity: > 98%. Potent, non-competitive mGlu1 receptor antagonist that displays 34-fold selectivity over mGlu5 (IC50 values are 10 and 342 nM respectively). Displays no significant activity at a range of other GPCRs, ion channels and transporters. ... 10mg 3060 TOCRIS BIOSCIENCE More Info
A 922500 Purity: > 98%. Diacyl glycerolacyltransferase 1 (DGAT-1) inhibitor (IC50 values are 7 and 24 nM at human and mouse DGAT-1 respectively) that is devoid of activity at DGAT-2, ACAT1 or ACAT2. Induces significant weight loss without altering food int... 10mg 3587 TOCRIS BIOSCIENCE More Info
A-71623 Purity: > 98%. Potent CCK1 agonist (IC50 = 3.7 nM) with 1200-fold selectivity over the CCK2 receptor. Suppresses food intake following central or peripheral administration. 1mg 2411 TOCRIS BIOSCIENCE More Info
A77 1726 Leflunomide metabolite that blocks TNF-dependent NF-kappaB activation and gene expression. Inhibits the activity of dihydroorotate dehydrogenase (DHO-DH; IC50 = 220 nM). Reported to reduce IFN-gamma-induced expression of iNOS in L929 fibroblasts. ... n/a 100128 CALBIOCHEM/EMD BIOSCIENCES More Info
A-779 Purity: > 95% 1 mg 06-271-83027 GENWAY BIOTECH INC. More Info
AA2 n/a n/a n/a NIH AIDS RESEARCH & REAGENTS More Info
AA 2414 Purity: > 98%. Thromboxane A2 (TP) receptor antagonist. Antiasthmatic agent; inhibits platelet aggregation and bronchoconstriction induced by a TXA2 mimetic in guinea pigs. 50mg 3025 TOCRIS BIOSCIENCE More Info
AA 2414 Purity: > 98%. Thromboxane A2 (TP) receptor antagonist. Antiasthmatic agent; inhibits platelet aggregation and bronchoconstriction induced by a TXA2 mimetic in guinea pigs. 10mg 3025 TOCRIS BIOSCIENCE More Info
AACOCF3 Purity: > 98%. Inhibitor of cytosolic (85 kDa) phospholipase A2. Also inhibits fatty acid amide hydrolase (FAAH, anandamide amidase) in vitro. 25mg 1462 TOCRIS BIOSCIENCE More Info
AACOCF3 Purity: > 98%. Inhibitor of cytosolic (85 kDa) phospholipase A2. Also inhibits fatty acid amide hydrolase (FAAH, anandamide amidase) in vitro. 5mg 1462 TOCRIS BIOSCIENCE More Info
AACOCF3 A cell-permeable trifluoromethyl ketone analog of arachidonic acid. Potent and selective slow-binding inhibitor of cytosolic (85 kDa) phospholipase A2 (cPLA2; ~20 µM). Specific inhibition of cPLA2 activity by AACOCF3 partially inhibits TNF-i... n/a 100109 CALBIOCHEM/EMD BIOSCIENCES More Info
17-AAG Purity: > 98%. Inhibitor of heat shock protein 90 (Hsp90) chaperone activity, and an analog of geldanamycin (Cat. No. 1368). Subsequently inhibits the activity of oncogenic proteins such as p185erbB-2 (IC50 = 31 nM), N-ras, Ki-ras and c-Akt. Antit... 1mg 1515 TOCRIS BIOSCIENCE More Info
17-AAG A less toxic, potent, synthetic derivative of the ansamycin benzoquinone antibiotic Geldanamycin, Streptomyces hygroscopicus (Cat. No. 345805) that binds to Hsp90 (EC50 = 7.2 µM) and regulates its function. Induces apoptosis and displays ant... n/a 100068 CALBIOCHEM/EMD BIOSCIENCES More Info
AAPH A heat-sensitive, water-soluble, free radical initiator that induces oxidative stress by causing cellular damage associated with lipid peroxidation, protein modification, hemoglobin oxidation, and DNA strand breakage. Reported to induce apoptosis ... n/a 100110 CALBIOCHEM/EMD BIOSCIENCES More Info
ABS 205 Purity: > 98%. Orally active valproic acid (Cat No. 2815) derivative that exhibits teratogenic and neuroprotective activity. Upregulates neural cell adhesion molecule (NCAM) expression, activates PPARdelta (IC50 = 0.6 mM) and increases Hoxa1 expre... 10mg 2721 TOCRIS BIOSCIENCE More Info
ABS 205 Purity: > 98%. Orally active valproic acid (Cat No. 2815) derivative that exhibits teratogenic and neuroprotective activity. Upregulates neural cell adhesion molecule (NCAM) expression, activates PPARdelta (IC50 = 0.6 mM) and increases Hoxa1 expre... 50mg 2721 TOCRIS BIOSCIENCE More Info
Abltide n/a 1 mg 12-493 MILLIPORE More Info
ABTS 2 g; 2,2'-Azino-di-[3-ethylben zthiazoline sulfonate (6)] diammonium salt, crystals. Formula: C18H16N4O6S4-(NH4)2Molecu lar weight: ABTS: Mr = 514.6, ABTS-(NH4)2: Mr = 548.7Solubility: soluble in water (c = 50 mg/ml)Note: The green color is due to f... n/a 10102946001 ROCHE APPLIED SCIENCE More Info
9-AC Purity: > 99%. Cl- transport inhibitor with a moderate to strong inhibitory action on PKA activated cardiac IcI. 100mg 0963 TOCRIS BIOSCIENCE More Info
AC 187 Purity: > 98%. Orally active, potent amylin receptor antagonist (IC50 = 0.48 nM) that displays 38-fold and 400-fold selectivity over calcitonin and CGRP receptors respectively. Blocks amyloid beta-induced neurotoxicity by attenuating the activatio... 500µg 3419 TOCRIS BIOSCIENCE More Info
AC 45594 Purity: > 99%. Selective inverse agonist at the orphan nuclear receptor steroidogenic factor-1 (SF-1) (IC50= 50-100 nM). Displays no activity at estrogen, LRH-1, ROR, ERR or Nurr receptors. Inhibits SFRE-mediated transcription. 10mg 3043 TOCRIS BIOSCIENCE More Info
AC 45594 Purity: > 99%. Selective inverse agonist at the orphan nuclear receptor steroidogenic factor-1 (SF-1) (IC50= 50-100 nM). Displays no activity at estrogen, LRH-1, ROR, ERR or Nurr receptors. Inhibits SFRE-mediated transcription. 50mg 3043 TOCRIS BIOSCIENCE More Info
AC 55541 Purity: > 97%. Potent and selective protease-activated receptor 2 (PAR2) agonist (pEC50 = 6.7) that displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation. Stimulates cell proliferation, P... 10mg 3369 TOCRIS BIOSCIENCE More Info
AC 55541 Purity: > 97%. Potent and selective protease-activated receptor 2 (PAR2) agonist (pEC50 = 6.7) that displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation. Stimulates cell proliferation, P... 50mg 3369 TOCRIS BIOSCIENCE More Info
AC 55649 Purity: > 99%. Potent, isoform-selective RARbeta2 receptor agonist (pEC50 values are 6.9, 5.7 and 5.6 at RARbeta2, RARbeta1 and RARalpha respectively) that displays 100-fold selectivity versus other retinoid receptors. Inhibits proliferation of th... 10mg 2436 TOCRIS BIOSCIENCE More Info
AC 55649 Purity: > 99%. Potent, isoform-selective RARbeta2 receptor agonist (pEC50 values are 6.9, 5.7 and 5.6 at RARbeta2, RARbeta1 and RARalpha respectively) that displays 100-fold selectivity versus other retinoid receptors. Inhibits proliferation of th... 50mg 2436 TOCRIS BIOSCIENCE More Info
Ac2-12 Purity: > 98%. Annexin/lipocortin 1-mimetic peptide; inhibits leukocyte extravasation. Reduces neutrophil adhesion and emigration, and promotes detachment of neutrophils from activated mesenteric endothelium in mice in vivo. 1mg 1846 TOCRIS BIOSCIENCE More Info
Ac2-26 Purity: > 98%. Annexin/lipocortin 1-mimetic peptide; inhibits leukocyte extravasation. Reduces neutrophil adhesion and emigration, and promotes detachment of neutrophils from activated mesenteric endothelium in mice in vivo. Anti-inflammatory. 500µg 1845 TOCRIS BIOSCIENCE More Info
Ac9-25 Purity: > 98%. N-terminal peptide of Annexin I (AI/Lipocortin I) that inhibits leukocyte extravasation. Acts as a formyl peptide receptor 1 (FPR1) ligand and stimulates neutrophil NADPH oxidase activation. 1mg 3231 TOCRIS BIOSCIENCE More Info
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