| A 205804 |
Selective inhibitor of E-selectin and ICAM-1 expression (IC50 values are 20, 25 and > 1000 nM for TNF- α-induced E-selectin, ICAM-1 and VCAM-1 expression respectively). Effective inhibitor of cell-cell adhesion in an in vitro flow experim... |
10mg, 50mg |
2524 |
TOCRIS BIOSCIENCE |
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| A 803467 |
Selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively). Shows no significant activity against TRPV1, P2X2/3, CaV2.2 and KCNQ2/3 channels. Anti... |
10mg, 50mg |
2976 |
TOCRIS BIOSCIENCE |
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| A 83-01 |
Selective inhibitor of TGF- β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF- β-induced ep... |
10mg, 50mg |
2939 |
TOCRIS BIOSCIENCE |
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| AA2 |
n/a |
n/a |
n/a |
NIH AIDS RESEARCH & REAGENTS |
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| AA 2414 |
Thromboxane A2 (TP) receptor antagonist. Anti-asthmatic agent; inhibits platelet aggregation and bronchoconstriction induced by a TXA2 mimetic in guinea pigs. |
10mg, 50mg |
3025 |
TOCRIS BIOSCIENCE |
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| AACOCF3 |
A cell-permeable trifluoromethyl ketone analog of arachidonic acid. Potent and selective slow-binding inhibitor of cytosolic (85 kDa) phospholipase A2 (cPLA2; ~20 µM). Specific inhibition of cPLA2 activity by AACOCF3 partially inhibits TNF-i... |
n/a |
100109 |
CALBIOCHEM/EMD BIOSCIENCES |
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| AACOCF3 |
Inhibitor of cytosolic (85 kDa) phospholipase A2. Also inhibits fatty acid amide hydrolase (FAAH, anandamide amidase) in vitro. |
5mg, 25mg |
1462 |
TOCRIS BIOSCIENCE |
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| 17-AAG |
n/a |
1 mg |
HPK-101J |
ASSAY DESIGNS INC. |
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| 17-AAG |
A less toxic, potent, synthetic derivative of the ansamycin benzoquinone antibiotic Geldanamycin, Streptomyces hygroscopicus (Cat. No. 345805) that binds to Hsp90 (EC50 = 7.2 µM) and regulates its function. Induces apoptosis and displays ant... |
n/a |
100068 |
CALBIOCHEM/EMD BIOSCIENCES |
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| 17-AAG |
Inhibitor of heat shock protein 90 (Hsp90) chaperone activity, and an analogue of geldanamycin (Cat. No. 1368). Subsequently inhibits the activity of oncogenic proteins such as p185erbB-2 (IC50 = 31 nM), N-ras, Ki-ras and c-Akt. Antitumour in vivo. |
1mg |
1515 |
TOCRIS BIOSCIENCE |
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| AAPH |
A heat-sensitive, water-soluble, free radical initiator that induces oxidative stress by causing cellular damage associated with lipid peroxidation, protein modification, hemoglobin oxidation, and DNA strand breakage. Reported to induce apoptosis ... |
n/a |
100110 |
CALBIOCHEM/EMD BIOSCIENCES |
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| Abamectin |
Mixture of avermectins, containing at least 80% of avermectin B1a (C48H72O14) and not more than 20% of avermectin B1b (C47H70O14). Used as acaricide, insecticide.Melting Point: 150-155?CSolubility: Acetone, Chloroform, Cyclohexanone, Ethanol, Meth... |
10mg |
A0003-01 |
UNITED STATES BIOLOGICAL |
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| Abl 1 |
n/a |
n/a |
SE-290 |
BIOMOL INTERNATIONAL, L.P. |
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| Abltide |
peptide substrate |
1mg |
A02-58 |
SIGNALCHEM |
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| Abltide |
n/a |
1 mg |
12-493 |
MILLIPORE |
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| ABTS |
2 g; 2,2'-Azino-di-[3-ethylben zthiazoline sulfonate (6)] diammonium salt, crystals. Formula: C18H16N4O6S4-(NH4)2Molecu lar weight: ABTS: Mr = 514.6, ABTS-(NH4)2: Mr = 548.7Solubility: soluble in water (c = 50 mg/ml)Note: The green color is due to f... |
n/a |
10102946001 |
ROCHE APPLIED SCIENCE |
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| 9-AC |
Cl- transport inhibitor with a moderate to strong inhibitory action on PKA activated cardiac IcI. |
100mg |
0963 |
TOCRIS BIOSCIENCE |
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| AC 45594 |
Selective inverse agonist at the orphan nuclear receptor steroidogenic factor-1 (SF-1) (IC50= 50-100 nM). Displays no activity at estrogen, LRH-1, ROR, ERR or Nurr receptors. Inhibits SFRE-mediated transcription. |
10mg, 50mg |
3043 |
TOCRIS BIOSCIENCE |
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| AC 55649 |
Potent, isoform-selective RAR β2 receptor agonist (pEC50 = 6.9) that displays 100-fold selectivity versus other retinoid receptors. Inhibits proliferation of the breast cancer cell line MCF-7. |
10mg, 50mg |
2436 |
TOCRIS BIOSCIENCE |
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| ACA |
A cell-permeable inhibitor of phospholipase A2 that blocks epinephrine-stimulated thromboxane production in platelets. Inhibits ATP-stimulated phosphatidylcholine (PC) secretion in alveolar type II cells. Also blocks phorbol ester and A23187-induc... |
n/a |
104550 |
CALBIOCHEM/EMD BIOSCIENCES |
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