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Records 21 - 40 of 132,619
Name Description Size Catalog # Supplier  
A 205804 Selective inhibitor of E-selectin and ICAM-1 expression (IC50 values are 20, 25 and > 1000 nM for TNF- α-induced E-selectin, ICAM-1 and VCAM-1 expression respectively). Effective inhibitor of cell-cell adhesion in an in vitro flow experim... 10mg, 50mg 2524 TOCRIS BIOSCIENCE More Info
A 803467 Selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively). Shows no significant activity against TRPV1, P2X2/3, CaV2.2 and KCNQ2/3 channels. Anti... 10mg, 50mg 2976 TOCRIS BIOSCIENCE More Info
A 83-01 Selective inhibitor of TGF- β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF- β-induced ep... 10mg, 50mg 2939 TOCRIS BIOSCIENCE More Info
AA2 n/a n/a n/a NIH AIDS RESEARCH & REAGENTS More Info
AA 2414 Thromboxane A2 (TP) receptor antagonist. Anti-asthmatic agent; inhibits platelet aggregation and bronchoconstriction induced by a TXA2 mimetic in guinea pigs. 10mg, 50mg 3025 TOCRIS BIOSCIENCE More Info
AACOCF3 A cell-permeable trifluoromethyl ketone analog of arachidonic acid. Potent and selective slow-binding inhibitor of cytosolic (85 kDa) phospholipase A2 (cPLA2; ~20 µM). Specific inhibition of cPLA2 activity by AACOCF3 partially inhibits TNF-i... n/a 100109 CALBIOCHEM/EMD BIOSCIENCES More Info
AACOCF3 Inhibitor of cytosolic (85 kDa) phospholipase A2. Also inhibits fatty acid amide hydrolase (FAAH, anandamide amidase) in vitro. 5mg, 25mg 1462 TOCRIS BIOSCIENCE More Info
17-AAG n/a 1 mg HPK-101J ASSAY DESIGNS INC. More Info
17-AAG A less toxic, potent, synthetic derivative of the ansamycin benzoquinone antibiotic Geldanamycin, Streptomyces hygroscopicus (Cat. No. 345805) that binds to Hsp90 (EC50 = 7.2 µM) and regulates its function. Induces apoptosis and displays ant... n/a 100068 CALBIOCHEM/EMD BIOSCIENCES More Info
17-AAG Inhibitor of heat shock protein 90 (Hsp90) chaperone activity, and an analogue of geldanamycin (Cat. No. 1368). Subsequently inhibits the activity of oncogenic proteins such as p185erbB-2 (IC50 = 31 nM), N-ras, Ki-ras and c-Akt. Antitumour in vivo. 1mg 1515 TOCRIS BIOSCIENCE More Info
AAPH A heat-sensitive, water-soluble, free radical initiator that induces oxidative stress by causing cellular damage associated with lipid peroxidation, protein modification, hemoglobin oxidation, and DNA strand breakage. Reported to induce apoptosis ... n/a 100110 CALBIOCHEM/EMD BIOSCIENCES More Info
Abamectin Mixture of avermectins, containing at least 80% of avermectin B1a (C48H72O14) and not more than 20% of avermectin B1b (C47H70O14). Used as acaricide, insecticide.Melting Point: 150-155?CSolubility: Acetone, Chloroform, Cyclohexanone, Ethanol, Meth... 10mg A0003-01 UNITED STATES BIOLOGICAL More Info
Abl 1 n/a n/a SE-290 BIOMOL INTERNATIONAL, L.P. More Info
Abltide peptide substrate 1mg A02-58 SIGNALCHEM More Info
Abltide n/a 1 mg 12-493 MILLIPORE More Info
ABTS 2 g; 2,2'-Azino-di-[3-ethylben zthiazoline sulfonate (6)] diammonium salt, crystals. Formula: C18H16N4O6S4-(NH4)2Molecu lar weight: ABTS: Mr = 514.6, ABTS-(NH4)2: Mr = 548.7Solubility: soluble in water (c = 50 mg/ml)Note: The green color is due to f... n/a 10102946001 ROCHE APPLIED SCIENCE More Info
9-AC Cl- transport inhibitor with a moderate to strong inhibitory action on PKA activated cardiac IcI. 100mg 0963 TOCRIS BIOSCIENCE More Info
AC 45594 Selective inverse agonist at the orphan nuclear receptor steroidogenic factor-1 (SF-1) (IC50= 50-100 nM). Displays no activity at estrogen, LRH-1, ROR, ERR or Nurr receptors. Inhibits SFRE-mediated transcription. 10mg, 50mg 3043 TOCRIS BIOSCIENCE More Info
AC 55649 Potent, isoform-selective RAR β2 receptor agonist (pEC50 = 6.9) that displays 100-fold selectivity versus other retinoid receptors. Inhibits proliferation of the breast cancer cell line MCF-7. 10mg, 50mg 2436 TOCRIS BIOSCIENCE More Info
ACA A cell-permeable inhibitor of phospholipase A2 that blocks epinephrine-stimulated thromboxane production in platelets. Inhibits ATP-stimulated phosphatidylcholine (PC) secretion in alveolar type II cells. Also blocks phorbol ester and A23187-induc... n/a 104550 CALBIOCHEM/EMD BIOSCIENCES More Info
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Records 21 - 40 of 132,619
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