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Name Description Size Catalog # Supplier  
AG 18 Inhibitor of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR) kinase (IC50 values are 35 and 25 µM respectively). Inhibits EGF-stimulated cell proliferation. Also acts as a mitochondrial uncoupler t... 10mg 0493 TOCRIS BIOSCIENCE More Info
AG 18 Inhibitor of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR) kinase (IC50 values are 35 and 25 µM respectively). Inhibits EGF-stimulated cell proliferation. Also acts as a mitochondrial uncoupler t... 50mg 0493 TOCRIS BIOSCIENCE More Info
AG 213 Epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR) kinase inhibitor (IC50 values are 2.4 and 3 µM respectively). Stimulates microtubule polymerization and promotes neurite outgrowth > 17-fold over bas... 10mg 0503 TOCRIS BIOSCIENCE More Info
AG 213 Epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR) kinase inhibitor (IC50 values are 2.4 and 3 µM respectively). Stimulates microtubule polymerization and promotes neurite outgrowth > 17-fold over bas... 50mg 0503 TOCRIS BIOSCIENCE More Info
AG 490 Selective inhibitor of EGF receptor tyrosine kinase (IC50 values are 2 and 13.5 µM for EGFR and ErbB2 respectively). Inhibitor of JAK2, JAK3/STAT, JAK3/AP-1 and JAK3/MAPK pathways and potently inhibits cytokine-independent cell growth in vit... 10mg 0414 TOCRIS BIOSCIENCE More Info
AG 490 Selective inhibitor of EGF receptor tyrosine kinase (IC50 values are 2 and 13.5 µM for EGFR and ErbB2 respectively). Inhibitor of JAK2, JAK3/STAT, JAK3/AP-1 and JAK3/MAPK pathways and potently inhibits cytokine-independent cell growth in vit... 50mg 0414 TOCRIS BIOSCIENCE More Info
AG 494 Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.7 µM). Selective over ErbB2, PDGFR and insulin receptor kinase (IC50 values are 42, 6 and > 100 µM respectively). Purity > 98% 10mg 0619 TOCRIS BIOSCIENCE More Info
AG 494 Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.7 µM). Selective over ErbB2, PDGFR and insulin receptor kinase (IC50 values are 42, 6 and > 100 µM respectively). Purity > 98% 50mg 0619 TOCRIS BIOSCIENCE More Info
AG 555 Potent epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 0.7 µM) that displays 50-fold and >140-fold selectivity over ErbB2 and insulin receptor kinase respectively. Induce G1 growth arrest selectively in transformed cells (IC... 10mg 0618 TOCRIS BIOSCIENCE More Info
AG 555 Potent epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 0.7 µM) that displays 50-fold and >140-fold selectivity over ErbB2 and insulin receptor kinase respectively. Induce G1 growth arrest selectively in transformed cells (IC... 50mg 0618 TOCRIS BIOSCIENCE More Info
AG 556 Epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 1.1 µM). Selective over ErbB2 (IC50 > 500 µM). Purity > 98% 10mg 0616 TOCRIS BIOSCIENCE More Info
AG 556 Epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 1.1 µM). Selective over ErbB2 (IC50 > 500 µM). Purity > 98% 50mg 0616 TOCRIS BIOSCIENCE More Info
AG 825 Selective ErbB2 inhibitor (IC50 values are 0.15 and 19 mM at ErbB2 and ErbB1 respectively). Preferentially triggers p38 MAP kinase-dependent apoptosis in androgen-independent prostate cancer cells. Purity > 98% 10mg 1555 TOCRIS BIOSCIENCE More Info
AG 825 Selective ErbB2 inhibitor (IC50 values are 0.15 and 19 mM at ErbB2 and ErbB1 respectively). Preferentially triggers p38 MAP kinase-dependent apoptosis in androgen-independent prostate cancer cells. Purity > 98% 50mg 1555 TOCRIS BIOSCIENCE More Info
AG 99 Epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 10 µM) that is selective over insulin receptor kinase. Blocks tyrosine phosphorylation of p145met and promotes cell death of normal and cancer cells via activation of caspase-l... 10mg 0497 TOCRIS BIOSCIENCE More Info
AG 99 Epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 10 µM) that is selective over insulin receptor kinase. Blocks tyrosine phosphorylation of p145met and promotes cell death of normal and cancer cells via activation of caspase-l... 50mg 0497 TOCRIS BIOSCIENCE More Info
AG 1024 A cell-permeable, reversible, substrate competitive, and specific inhibitor of insulin-like growth factor-1 (IGF-1) and insulin receptor tyrosine kinase activity. Exhibits lower IC50 values for IGF-1 than for the insulin receptor. Also inhibits in... n/a 121767 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 112 A cell-permeable, reversible, substrate competitive inhibitor of epidermal growth factor receptor tyrosine kinase (IC50 = 125 nM). n/a 658440 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 126 A cell-permeable inhibitor of lipopolysaccharide (LPS)-induced synthesis of tumor necrosis factor-α and nitric oxide in murine peritoneal macrophages. Blocks LPS-induced tyrosine phosphorylation of a p42MAPK/ERK2 protein substrate. Reduces t... n/a 658452 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 1295 A cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor (PDGF) receptor kinase (IC50 = 500 nM) and PDGF-dependent DNA synthesis (IC50 = 2.5 µM) in Swiss/3T3 cells. Has no effect on EGF recepto... n/a 658550 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 1296 Similar to but more potent than AG 1295 (Cat. No. 658550). A cell-permeable, reversible, and ATP-competitive, inhibitor of PDGF receptor kinase and blocks signaling of human PDGF α-receptors (IC50 = 1.0 µM) and β-receptors (IC50 =... n/a 658551 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 1387 A reversible and substrate competitive 5-iodo analog of tyrphostin AG 555 (Cat. No. 658404) that displays anticancer and antiviral properties. Reported to be more cell-permeable and potent than AG 555 as an inhibitor of protein tyrosine kinase and... n/a 658520 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 1433 A potent, cell-permeable, reversible, and specific inhibitor of the PDGF-β receptor kinase (IC50 = 5.0 µM) and of KDR/Flk-1/VEGF Receptor 2 (IC50 = 9.3 µM). Also acts as an angiogenesis inhibitor. n/a 658553 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 1478 A cell-permeable, reversible, ATP-competitive, highly potent and selective inhibitor of epidermal growth factor receptor kinase (IC50 = 3 nM) versus HER2-neu (IC50 >100 µM) and platelet-derived growth factor receptor kinase (IC50 >100 ... n/a 658552 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 17 Anti-proliferative agent that acts as a selective inhibitor of the platelet-derived growth factor receptor tyrosine kinase (IC50 = 500 nM). A potent, cell-permeable, reversible, and substrate competitive inhibitor of TNF-induced tyrosine phosphory... n/a 658425 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 18 A broad-spectrum protein tyrosine kinase inhibitor. Inhibits epidermal growth factor receptor autophosphorylation (IC50 = 40 µM) and the GTPase activity of transducin (IC50 = 10 µM). Inhibits aldosterone secretion in response to Angiot... n/a 658395 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 213 A cell-permeable, reversible, substrate competitive inhibitor of epidermal growth factor receptor tyrosine kinase activity (IC50 = 2.4 µM). Blocks HT-29 colon cancer cell proliferation and induces non-apoptotic cell death. Inhibits capacitat... n/a 658405 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 30 A potent, cell-permeable, reversible, and substrate competitive protein tyrosine kinase (PTK) inhibitor specific for c-ErbB. Inhibits activation of STAT5 by c-ErbB in primary erythroblasts. Also causes induction of the differentiated phenotype in ... n/a 121760 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 43 Useful negative control for tyrphostins (IC50 = 6.5 mM) for epidermal growth factor receptor tyrosine kinase activity. n/a 658450 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 490 A cell-permeable, reversible, substrate competitive, and potent inhibitor of epidermal growth factor receptor kinase autophosphorylation (IC50 = 100 nM). Inhibition of JAK2 by AG 490 selectively blocks leukemic cell growth in vitro and in vivo by ... n/a 658401 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 538 A potent, cell-premeable, reversible, and competitive inhibitor of IGF-1 receptor kinase (IC50 = 400 nM). Reaction is competitive with respect to IGF-1R substrate. Also inhibits the phosphorylation of PTK substrate poly(Glu,Tyr) by IGF-1R, IR, EGF... n/a 658403 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 556 Selectively inhibits epidermal growth factor receptor kinase autophosphorylation (IC50 = 5 µM) over HER1/2 autophosphorylation. Also blocks LPS-induced TNF-α production and attentuates LPS-induced hypotension in rats. n/a 658415 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 82 A cell-permeable, reversible, and competitive inhibitor of substrate binding on protein tyrosine kinases. Inhibits epidermal growth factor receptor tyrosine kinase (IC50 = 3 µM) and the GTPase activity of transducin (IC50 = 7 µM). Inhi... n/a 658400 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 825 A potent, cell-premeable, reversible, substrate competitive, and selective inhibitor of HER2 (neu/ErbB2; IC50 = 0.35 µM) relative to HER1 (IC50 = 19 µM) autophosphorylation. The inhibition is competitive with respect to ATP binding. En... n/a 121765 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 879 A cell-permeable, reversible, and substrate competitive inhibitor of nerve growth factor (NGF)-dependent p140c-trk tyrosine phosphorylation (EC50 = 10 µM) as well as NGF-induced phospholipase C-γ1 phosphorylation. Also blocks NGF-induc... n/a 658460 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 9 An inactive compound that can be used as a negative control for inhibition of EGFR (IC50 >1250 µM for EGFR kinase). Has been shown to inhibit IL-2 stimulated Tyk-2 phosphorylation in ConA-activated T cells. n/a 658390 CALBIOCHEM/EMD BIOSCIENCES More Info
AGAR n/a n/a n/a AMERICAN BIOANALYTICAL More Info
Agar Suitable for inclusion in culture media. n/a 12177 CALBIOCHEM/EMD BIOSCIENCES More Info
AGGRECAN HPLC: >99% 0.05 mg 06-783-79463 GENWAY BIOTECH INC. More Info
AGK 2 Selective inhibitor of SIRT2 (IC50 = 3.5 µM). Displays no activity at SIRT1 and SIRT3 at concentrations up to 40 µM. Reduces alpha-synuclein-mediated toxicity in in vitro and in vivo models of Parkinson's disease. Purity > 98% 10mg 3233 TOCRIS BIOSCIENCE More Info
AGK 2 Selective inhibitor of SIRT2 (IC50 = 3.5 µM). Displays no activity at SIRT1 and SIRT3 at concentrations up to 40 µM. Reduces alpha-synuclein-mediated toxicity in in vitro and in vivo models of Parkinson's disease. Purity > 98% 50mg 3233 TOCRIS BIOSCIENCE More Info
Agmatine n/a 1.0 mg AG085 CELL SCIENCES INC. More Info
AGR2 Recombinant Human Anterior Gradient Protein 2 Homolog 10µg/50µg/1mg PRO- 580 PROSPEC-TANY TECHNOGENE LTD. More Info
AGR 2 Purity: >= 95% by SDS PAGE 0.1 mg 10-002-38092 GENWAY BIOTECH INC. More Info
AGR 2 Purity: >= 95% by SDS PAGE 1 mg 10-002-38092 GENWAY BIOTECH INC. More Info
AGRP Recombinant Human Agouti-Related Protein 2µg/10µg/1mg HOR- 283 PROSPEC-TANY TECHNOGENE LTD. More Info
AH 6809 Antagonist at prostaglandin EP1 (pA2 = 6.8 ) and EP2 (Ki = 350 nM) receptors. Also weakly inhibits DP receptors (pA2 = 4.45). Purity > 99% 50mg 0671 TOCRIS BIOSCIENCE More Info
AH 6809 Antagonist at prostaglandin EP1 (pA2 = 6.8 ) and EP2 (Ki = 350 nM) receptors. Also weakly inhibits DP receptors (pA2 = 4.45). Purity > 99% 10mg 0671 TOCRIS BIOSCIENCE More Info
AHA1 Recombinant Human Activator of HSP90 ATPase-1 10µg/50µg/1mg HSP- 013 PROSPEC-TANY TECHNOGENE LTD. More Info
AHSG Purity: >95% (SDS-PAGE analyzed). 0.01 mg 11-663-46096 GENWAY BIOTECH INC. More Info
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Records 201 - 250 of 186,906
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