Page 9 of 6,631
Records 161 - 180 of 132,619
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Name Description Size Catalog # Supplier  
AG 538 A potent, competitive inhibitor of IGF-1 receptor kinase (IC50 = 400 nM). Reaction is competitive with respect to IGF-1R substrate. Also inhibits the phosphorylation of PTK substrate poly(Glu,Tyr) by IGF-1R, IR, EGF-R, and Src (IC50 = 60 nM, 113 n... n/a 658403 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 555 A potent inhibitor of epidermal growth factor (EGF) receptor kinase autophosphorylation (IC50 = 700 nM). Exhibits opposite potency profiles with AG 527 (Cat. No. 658402) for EGF receptor autophosphorylation versus poly-GAT substrate phosphorylation. n/a 658404 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 556 Selectively inhibits epidermal growth factor receptor kinase autophosphorylation (IC50 = 5 µM) over HER1/2 autophosphorylation. Also blocks LPS-induced TNF-α production and attentuates LPS-induced hypotension in rats. n/a 658415 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 82 A cell-permeable, competitive inhibitor of substrate binding on protein tyrosine kinases. Inhibits epidermal growth factor receptor tyrosine kinase (IC50 = 3 µM) and the GTPase activity of transducin (IC50 = 7 µM). Inhibits neuromedin ... n/a 658400 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 825 A potent and selective inhibitor of HER2 (neu/ErbB2; IC50 = 0.35 µM) relative to HER1 (IC50 = 19 µM) autophosphorylation. The inhibition is competitive with respect to ATP binding. Enhances chemosensitivity in non-small cell lung cance... n/a 121765 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 879 Inhibits nerve growth factor (NGF)-dependent p140c-trk tyrosine phosphorylation (EC50 = 10 µM) as well as NGF-induced phospholipase C-γ1 phosphorylation. Also blocks NGF-induced neurite outgrowth in PC12 cells. Does not affect the tyro... n/a 658460 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 9 An inactive compound that can be used as a negative control for inhibition of EGFR (IC50 >1250 µM for EGFR kinase). Has been shown to inhibit IL-2 stimulated Tyk-2 phosphorylation in ConA-activated T cells. n/a 658390 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 957 A potent tyrosine kinase inhibitor. Selectively blocks the tyrosine kinase activity of human p210bcr-abl (Ki = 750 nM) over p140c-abl (Ki = 10 µM). Also decreases p210bcr-abl phosphorylation in viable K562 cells at concentrations and duratio... n/a 121761 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 99 Inhibits epidermal growth factor (EGF) receptor tyrosine kinase (IC50 = 10 µM) and EGF-dependent cell proliferation. Inhibits EGFR phosphorylation and ERK1 and ERK2 activities. n/a 658430 CALBIOCHEM/EMD BIOSCIENCES More Info
AG 045572 Selective gonadotropin-releasing hormone (GnRH) receptor antagonist (Ki values are 2.2, 3.8 and 6.0 nM for mouse, rat and human receptors respectively). Suppresses testosterone and luteinising hormone (LH) levels in vivo. 1mg, 10mg 2730 TOCRIS BIOSCIENCE More Info
AG 18 Inhibitor of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR) kinase (IC50 values are 35 and 25 μM respectively). Inhibits EGF-stimulated cell proliferation. 10mg, 50mg 0493 TOCRIS BIOSCIENCE More Info
AG 213 A potent inhibitor of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR) kinase (IC50 values are 2.4 and 3 μM respectively). Also inhibits protein kinase C (IC50 = 60 μM). 10mg, 50mg 0503 TOCRIS BIOSCIENCE More Info
AG 490 Selective inhibitor of EGF receptor tyrosine kinase (IC50 values are 2 and 13.5 μM for EGFR and Her2-neu respectively). Inhibitor of Jak2, Jak3/STAT, Jak3/AP-1 and Jak3/MAPK pathways. 10mg, 50mg 0414 TOCRIS BIOSCIENCE More Info
AG 494 Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.7 μM). Selective over Her2-neu, PDGFR and insulin receptor kinase (IC50 values are 42, 6 and > 100 μM respectively). 10mg, 50mg 0619 TOCRIS BIOSCIENCE More Info
AG 555 Potent epidermal growth factor receptor (EGFR) kinase (IC50 = 0.7 μM). Selective over Her2-neu and insulin receptor kinase (IC50 values are 35 and > 100 μM respectively). 10mg, 50mg 0618 TOCRIS BIOSCIENCE More Info
AG 556 Epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 1.1 μM). Selective over Her2-neu (IC50 > 500 μM). 10mg, 50mg 0616 TOCRIS BIOSCIENCE More Info
AG 825 Epidermal growth factor receptor (EGFR) kinase inhibitor. Selective for Her2 over Her1 (IC50 values are 0.15 and 19 mM respectively). Preferentially triggers p38 MAP kinase-dependent apoptosis in androgen-independent prostate cancer cells. 10mg, 50mg 1555 TOCRIS BIOSCIENCE More Info
AG 99 Epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 10 μM). Selective over insulin receptor kinase. 10mg, 50mg 0497 TOCRIS BIOSCIENCE More Info
AGAR n/a n/a n/a AMERICAN BIOANALYTICAL More Info
Agar Suitable for inclusion in culture media. n/a 12177 CALBIOCHEM/EMD BIOSCIENCES More Info
Page 9 of 6,631
Records 161 - 180 of 132,619
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