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Non-antibody Products (Kits, Proteins, Microbial Antigens, Tissues, Services, etc.) - Page 2 of 6,058
Page 2 of 6,058
Records 51 - 100 of 302,891
[1]  «  1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11  »  [6058]
Results per Page: 25 | 50 | 75 | 100
Name Description Size Catalog # Supplier  
AT 56 Orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS) (Ki = 75 µM, IC50 = 95 µM). Inhibits the production of PGD2 from PGH2 in vitro, with no effect on PGE2 or PGF2alpha production. Minimum Purity: > 99% 10mg 3531
TOCRIS BIOSCIENCE		 More Info
AT 56 Orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS) (Ki = 75 µM, IC50 = 95 µM). Inhibits the production of PGD2 from PGH2 in vitro, with no effect on PGE2 or PGF2alpha production. Minimum Purity: > 99% 50mg 3531
TOCRIS BIOSCIENCE		 More Info
A 582941 Selective alpha7 nAChR partial agonist; exhibits high affinity for both rat and human alpha7 receptors (Ki values are 10.8 and 16.7 nM respectively). Displays ~15-fold selectivity for alpha7 over 5-HT3 receptors (Ki = 150 nM for 5-HT3). Minimum Pu... 10mg 4341
TOCRIS BIOSCIENCE		 More Info
A 582941 Selective alpha7 nAChR partial agonist; exhibits high affinity for both rat and human alpha7 receptors (Ki values are 10.8 and 16.7 nM respectively). Displays ~15-fold selectivity for alpha7 over 5-HT3 receptors (Ki = 150 nM for 5-HT3). Minimum Pu... 50mg 4341
TOCRIS BIOSCIENCE		 More Info
AS 605240 PI 3-Kinase Inhibitor 10 mg 3578/10
R&D SYSTEMS, INC.		 More Info
AS 605240 PI 3-Kinase Inhibitor 50 mg 3578/50
R&D SYSTEMS, INC.		 More Info
AS 605240 Potent and selective inhibitor of PI 3-kinase gamma (PI3Kgamma) (IC50 = 8 nM). Displays 30-fold selectivity over PI3Kdelta and PI3Kbeta and 7.5-fold selectivity over PI3Kalpha. Suppresses the progression of joint inflammation and damage in both ly... 10mg 3578
TOCRIS BIOSCIENCE		 More Info
AS 605240 Potent and selective inhibitor of PI 3-kinase gamma (PI3Kgamma) (IC50 = 8 nM). Displays 30-fold selectivity over PI3Kdelta and PI3Kbeta and 7.5-fold selectivity over PI3Kalpha. Suppresses the progression of joint inflammation and damage in both ly... 50mg 3578
TOCRIS BIOSCIENCE		 More Info
A 740003 P2X Receptor Antagonist 10 mg 3701/10
R&D SYSTEMS, INC.		 More Info
A 740003 P2X Receptor Antagonist 50 mg 3701/50
R&D SYSTEMS, INC.		 More Info
A 740003 Potent, selective and competitive P2X7 receptor antagonist (IC50 values are 18 and 40 nM for rat and human receptors respectively). Displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100 µM. Reduces nocicep... 10mg 3701
TOCRIS BIOSCIENCE		 More Info
A 740003 Potent, selective and competitive P2X7 receptor antagonist (IC50 values are 18 and 40 nM for rat and human receptors respectively). Displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100 µM. Reduces nocicep... 50mg 3701
TOCRIS BIOSCIENCE		 More Info
A 769662 AMPK Activator 10 mg 3336/10
R&D SYSTEMS, INC.		 More Info
A 769662 AMPK Activator 50 mg 3336/50
R&D SYSTEMS, INC.		 More Info
A 769662 Potent, reversible AMP-activated protein kinase (AMPK) activator (EC50 = 0.8 µM) that displays selectivity towards beta1 subunit-containing heterotrimers. Inhibits fatty acid synthesis (IC50 = 3.2 µM) and decreases plasma glucose and t... 10mg 3336
TOCRIS BIOSCIENCE		 More Info
A 769662 Potent, reversible AMP-activated protein kinase (AMPK) activator (EC50 = 0.8 µM) that displays selectivity towards beta1 subunit-containing heterotrimers. Inhibits fatty acid synthesis (IC50 = 3.2 µM) and decreases plasma glucose and t... 50mg 3336
TOCRIS BIOSCIENCE		 More Info
A 803467 n/a 10 mg 2976/10
R&D SYSTEMS, INC.		 More Info
A 803467 n/a 50 mg 2976/50
R&D SYSTEMS, INC.		 More Info
A 803467 Selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively). Shows no significant activity against TRPV1, P2X2/3, CaV2.2 and KCNQ2/3 channels. Anti... 10mg 2976
TOCRIS BIOSCIENCE		 More Info
A 803467 Selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively). Shows no significant activity against TRPV1, P2X2/3, CaV2.2 and KCNQ2/3 channels. Anti... 50mg 2976
TOCRIS BIOSCIENCE		 More Info
A 80426 Adrenergic alpha-2 Receptor Antagonist 10 mg 2341/10
R&D SYSTEMS, INC.		 More Info
A 80426 Adrenergic alpha-2 Receptor Antagonist 50 mg 2341/50
R&D SYSTEMS, INC.		 More Info
A 83-01 A selective inhibitor of TGF-beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-beta-induced epithe... 1 mg 1725-1
BIOVISION, INC.		 More Info
A 83-01 TGF-beta Receptor Inhibitor 10 mg 2939/10
R&D SYSTEMS, INC.		 More Info
A 83-01 TGF-beta Receptor Inhibitor 50 mg 2939/50
R&D SYSTEMS, INC.		 More Info
A 83-01 Selective inhibitor of TGF-beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-beta-induced epitheli... 10mg 2939
TOCRIS BIOSCIENCE		 More Info
A 83-01 Selective inhibitor of TGF-beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-beta-induced epitheli... 50mg 2939
TOCRIS BIOSCIENCE		 More Info
A 839977 P2X Receptor Antagonist 10 mg 4232/10
R&D SYSTEMS, INC.		 More Info
A 839977 P2X Receptor Antagonist 50 mg 4232/50
R&D SYSTEMS, INC.		 More Info
A 839977 Potent P2X7 antagonist; blocks BzATP-evoked calcium influx at recombinant human, rat and mouse P2X7 receptors (IC50 values are 20, 42 and 150 nM respectively). Displays antinociceptive effects in rat and mice models of inflammatory pain. CNS penet... 10mg 4232
TOCRIS BIOSCIENCE		 More Info
A 839977 Potent P2X7 antagonist; blocks BzATP-evoked calcium influx at recombinant human, rat and mouse P2X7 receptors (IC50 values are 20, 42 and 150 nM respectively). Displays antinociceptive effects in rat and mice models of inflammatory pain. CNS penet... 50mg 4232
TOCRIS BIOSCIENCE		 More Info
A 841720 Group I mGluR Antagonist 10 mg 3060/10
R&D SYSTEMS, INC.		 More Info
A 841720 Group I mGluR Antagonist 50 mg 3060/50
R&D SYSTEMS, INC.		 More Info
A 841720 Potent, non-competitive mGlu1 receptor antagonist that displays 34-fold selectivity over mGlu5 (IC50 values are 10 and 342 nM respectively). Displays no significant activity at a range of other GPCRs, ion channels and transporters. Exhibits analge... 10mg 3060
TOCRIS BIOSCIENCE		 More Info
A 841720 Potent, non-competitive mGlu1 receptor antagonist that displays 34-fold selectivity over mGlu5 (IC50 values are 10 and 342 nM respectively). Displays no significant activity at a range of other GPCRs, ion channels and transporters. Exhibits analge... 50mg 3060
TOCRIS BIOSCIENCE		 More Info
A 887826 n/a 10 mg 4249/10
R&D SYSTEMS, INC.		 More Info
A 887826 n/a 50 mg 4249/50
R&D SYSTEMS, INC.		 More Info
A 887826 Potent voltage-dependent NaV1.8 channel blocker (IC50 = 11 nM in recombinant human NaV1.8 channels). Reduces tactile allodynia in neuropathic rat models. 3- and 28-fold more potent at NaV1.8 channels compared to NaV1.2 and NaV1.7 channels respecti... 10mg 4249
TOCRIS BIOSCIENCE		 More Info
A 887826 Potent voltage-dependent NaV1.8 channel blocker (IC50 = 11 nM in recombinant human NaV1.8 channels). Reduces tactile allodynia in neuropathic rat models. 3- and 28-fold more potent at NaV1.8 channels compared to NaV1.2 and NaV1.7 channels respecti... 50mg 4249
TOCRIS BIOSCIENCE		 More Info
92.1.7 n/a n/a n/a VIRCELL S.L. More Info
A 922500 Acyltransferase Inhibitor 10 mg 3587/10
R&D SYSTEMS, INC.		 More Info
A 922500 Diacylglycerol acyltransferase 1 (DGAT-1) inhibitor (IC50 values are 7 and 24 nM at human and mouse DGAT-1 respectively) that is devoid of activity at DGAT-2, ACAT1 or ACAT2. Induces significant weight loss without altering food intake, and decrea... 10mg 3587
TOCRIS BIOSCIENCE		 More Info
A 987306 Histamine H4 Receptor Antagonist 10 mg 3640/10
R&D SYSTEMS, INC.		 More Info
A 987306 Histamine H4 Receptor Antagonist 50 mg 3640/50
R&D SYSTEMS, INC.		 More Info
A 987306 Potent histamine H4 receptor antagonist (pKi values are 8.24 and 8.47 in human and rat H4 receptors respectively). Displays 162-fold, 620-fold, and > 1600-fold selectivity over human H3, H1 and H2 receptors. Blocks zymosan-induced neutrophil reflu... 10mg 3640
TOCRIS BIOSCIENCE		 More Info
A 987306 Potent histamine H4 receptor antagonist (pKi values are 8.24 and 8.47 in human and rat H4 receptors respectively). Displays 162-fold, 620-fold, and > 1600-fold selectivity over human H3, H1 and H2 receptors. Blocks zymosan-induced neutrophil reflu... 50mg 3640
TOCRIS BIOSCIENCE		 More Info
A2.01 n/a n/a n/a
NIH AIDS RESEARCH & REFERENCE REAGENT PROGRAM		 More Info
A3.01 n/a n/a n/a
NIH AIDS RESEARCH & REFERENCE REAGENT PROGRAM		 More Info
A549 n/a n/a n/a VIRCELL S.L. More Info
A-769662 A-769662 Purity is greater than 99%. 10 mg orb60992
BIORBYT LTD.		 More Info
Page 2 of 6,058
Records 51 - 100 of 302,891
[1]  «  1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11  »  [6058]
Results per Page: 25 | 50 | 75 | 100
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