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Non-antibody Products (Kits, Proteins, Microbial Antigens, Tissues, Services, etc.) - Page 1 of 3,029
Page 1 of 3,029
Records 1 - 100 of 302,891
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Name Description Size Catalog # Supplier  
AS 101 n/a 10 mg 2446/10
R&D SYSTEMS, INC.		 More Info
AS 101 n/a 50 mg 2446/50
R&D SYSTEMS, INC.		 More Info
AT 101 n/a 10 mg 3367/10
R&D SYSTEMS, INC.		 More Info
AT 101 n/a 50 mg 3367/50
R&D SYSTEMS, INC.		 More Info
AS 101 Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1alpha, IL-2 and TNF-alpha release. Minimum Purity: > 98% 50mg 2446
TOCRIS BIOSCIENCE		 More Info
AS 101 Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1alpha, IL-2 and TNF-alpha release. Minimum Purity: > 98% 10mg 2446
TOCRIS BIOSCIENCE		 More Info
AT 101 R-(-)-enantiomer of gossypol (Cat. No. 1964). Mimics the BH3 domains of Bcl-2, Bcl-XL and Mcl-1. Disrupts heterodimerization of Bcl-2 with proapoptotic family members. Induces apoptosis in vitro through activation of caspase-9; cytotoxic to multip... 10mg 3367
TOCRIS BIOSCIENCE		 More Info
AT 101 R-(-)-enantiomer of gossypol (Cat. No. 1964). Mimics the BH3 domains of Bcl-2, Bcl-XL and Mcl-1. Disrupts heterodimerization of Bcl-2 with proapoptotic family members. Induces apoptosis in vitro through activation of caspase-9; cytotoxic to multip... 50mg 3367
TOCRIS BIOSCIENCE		 More Info
A 1120 n/a 10 mg 3793/10
R&D SYSTEMS, INC.		 More Info
A 1120 n/a 50 mg 3793/50
R&D SYSTEMS, INC.		 More Info
A 1120 High affinity retinol-binding protein 4 (RBP4) ligand (Ki = 8.3 nM); non-retinoid. Selective against a range of different cellular targets. As efficacious as fenretinide (Cat. No. 1396) in the reduction of serum RBP4 and retinol. Displaces transth... 50mg 3793
TOCRIS BIOSCIENCE		 More Info
A 1120 High affinity retinol-binding protein 4 (RBP4) ligand (Ki = 8.3 nM); non-retinoid. Selective against a range of different cellular targets. As efficacious as fenretinide (Cat. No. 1396) in the reduction of serum RBP4 and retinol. Displaces transth... 10mg 3793
TOCRIS BIOSCIENCE		 More Info
AS 1269574 GPR119 Receptor Agonist 10 mg 4177/10
R&D SYSTEMS, INC.		 More Info
AS 1269574 GPR119 Receptor Agonist 50 mg 4177/50
R&D SYSTEMS, INC.		 More Info
AS 1269574 GPR119 receptor agonist (EC50 = 2.5 µM in HEK293 cells expressing human GPR119). Enhances insulin secretion stimulated by glucose in vivo. Orally available. Minimum Purity: > 98% 10mg 4177
TOCRIS BIOSCIENCE		 More Info
AS 1269574 GPR119 receptor agonist (EC50 = 2.5 µM in HEK293 cells expressing human GPR119). Enhances insulin secretion stimulated by glucose in vivo. Orally available. Minimum Purity: > 98% 50mg 4177
TOCRIS BIOSCIENCE		 More Info
S 18986 Positive allosteric modulator of AMPA receptors. Exhibits cognitive enhancing properties in rodent behavioral models. Brain penetrant. Minimum Purity: > 98% 10mg 3911
TOCRIS BIOSCIENCE		 More Info
S 18986 Positive allosteric modulator of AMPA receptors. Exhibits cognitive enhancing properties in rodent behavioral models. Brain penetrant. Minimum Purity: > 98% 50mg 3911
TOCRIS BIOSCIENCE		 More Info
AS 19 5-HT7 Receptor Agonist 10 mg 1968/10
R&D SYSTEMS, INC.		 More Info
AS 19 5-HT7 Receptor Agonist 50 mg 1968/50
R&D SYSTEMS, INC.		 More Info
AS 19 Potent 5-HT7 receptor agonist (IC50 = 0.83 nM). Enhances memory consolidation and reverses scopolamine- or dizocilpine-induced amnesia in vivo. Minimum Purity: > 98% 10mg 1968
TOCRIS BIOSCIENCE		 More Info
AS 19 Potent 5-HT7 receptor agonist (IC50 = 0.83 nM). Enhances memory consolidation and reverses scopolamine- or dizocilpine-induced amnesia in vivo. Minimum Purity: > 98% 50mg 1968
TOCRIS BIOSCIENCE		 More Info
AS 1949490 Inositol Phosphatase Inhibitor 10 mg 3718/10
R&D SYSTEMS, INC.		 More Info
AS 1949490 Inositol Phosphatase Inhibitor 50 mg 3718/50
R&D SYSTEMS, INC.		 More Info
AS 1949490 Selective SHIP2 (SH2 domain-containing inositol 5'-phosphatase 2) inhibitor (IC50 values are 0.34 µM and 0.62 µM for mouse and human respectively); displays approximately 30-fold affinity for SHIP2 over SHIP1. Increases insulin-induced... 10mg 3718
TOCRIS BIOSCIENCE		 More Info
AS 1949490 Selective SHIP2 (SH2 domain-containing inositol 5'-phosphatase 2) inhibitor (IC50 values are 0.34 µM and 0.62 µM for mouse and human respectively); displays approximately 30-fold affinity for SHIP2 over SHIP1. Increases insulin-induced... 50mg 3718
TOCRIS BIOSCIENCE		 More Info
A 205804 Cell Adhesion Inhibitor 10 mg 2524/10
R&D SYSTEMS, INC.		 More Info
A 205804 Cell Adhesion Inhibitor 50 mg 2524/50
R&D SYSTEMS, INC.		 More Info
A 205804 Selective inhibitor of E-selectin and ICAM-1 expression (IC50 values are 20, 25 and > 1000 nM for TNF-alpha-induced E-selectin, ICAM-1 and VCAM-1 expression respectively). Effective inhibitor of cell-cell adhesion in an in vitro flow experiment. M... 10mg 2524
TOCRIS BIOSCIENCE		 More Info
A 205804 Selective inhibitor of E-selectin and ICAM-1 expression (IC50 values are 20, 25 and > 1000 nM for TNF-alpha-induced E-selectin, ICAM-1 and VCAM-1 expression respectively). Effective inhibitor of cell-cell adhesion in an in vitro flow experiment. M... 50mg 2524
TOCRIS BIOSCIENCE		 More Info
S 24795 Nicotinic (a7) Receptor Agonist 10 mg 3518/10
R&D SYSTEMS, INC.		 More Info
S 24795 Nicotinic (a7) Receptor Agonist 50 mg 3518/50
R&D SYSTEMS, INC.		 More Info
S 24795 Partial agonist of alpha7 nAChR. Improves mnemonic function in aged mice for the treatment of aging-related memory disturbances. Displays more efficient memory-enhancing effects than memantine (Cat.No 0773) in Alzheimer's disease mouse models. Min... 10mg 3518
TOCRIS BIOSCIENCE		 More Info
S 24795 Partial agonist of alpha7 nAChR. Improves mnemonic function in aged mice for the treatment of aging-related memory disturbances. Displays more efficient memory-enhancing effects than memantine (Cat.No 0773) in Alzheimer's disease mouse models. Min... 50mg 3518
TOCRIS BIOSCIENCE		 More Info
AS 252424 PI 3-Kinase Inhibitor 10 mg 3671/10
R&D SYSTEMS, INC.		 More Info
AS 252424 Potent and selective inhibitor of PI 3-kinase gamma (IC50 values are 33 and 935 nM for PI3Kgamma and PI3Kalpha respectively). Minimum Purity: > 98% 10mg 3671
TOCRIS BIOSCIENCE		 More Info
S 25585 NPY Receptor Antagonist 10 mg 3432/10
R&D SYSTEMS, INC.		 More Info
S 25585 NPY Receptor Antagonist 50 mg 3432/50
R&D SYSTEMS, INC.		 More Info
S 25585 Potent neuropeptide Y (NPY) Y5 receptor antagonist (IC50 values are 5.4, > 1000, > 10 000 and > 10 000 nM at Y5, Y1, Y2 and Y4 receptors respectively) that displays no affinity for a wide range of other receptors. Does not produce a conditioned ta... 10mg 3432
TOCRIS BIOSCIENCE		 More Info
S 25585 Potent neuropeptide Y (NPY) Y5 receptor antagonist (IC50 values are 5.4, > 1000, > 10 000 and > 10 000 nM at Y5, Y1, Y2 and Y4 receptors respectively) that displays no affinity for a wide range of other receptors. Does not produce a conditioned ta... 50mg 3432
TOCRIS BIOSCIENCE		 More Info
A 286982 Integrin Receptor Inhibitor 10 mg 4228/10
R&D SYSTEMS, INC.		 More Info
A 286982 Integrin Receptor Inhibitor 50 mg 4228/50
R&D SYSTEMS, INC.		 More Info
A 286982 Potent inhibitor of the LFA-1/ICAM-1 interaction (IC50 values are 44 and 35 nM in LFA-1/ICAM-1 binding and LFA-1-mediated cell adhesion assays respectively). Minimum Purity: > 99% 10mg 4228
TOCRIS BIOSCIENCE		 More Info
A 286982 Potent inhibitor of the LFA-1/ICAM-1 interaction (IC50 values are 44 and 35 nM in LFA-1/ICAM-1 binding and LFA-1-mediated cell adhesion assays respectively). Minimum Purity: > 99% 50mg 4228
TOCRIS BIOSCIENCE		 More Info
293 n/a n/a n/a
NIH AIDS RESEARCH & REFERENCE REAGENT PROGRAM		 More Info
293 n/a n/a n/a VIRCELL S.L. More Info
S 32826 Autotaxin Inhibitor 10 mg 3404/10
R&D SYSTEMS, INC.		 More Info
S 32826 Inhibitor of autotaxin (IC50 = 9 nM). Displays similar inhibitory effects at all three autotaxin isoforms (alpha, beta and gamma). Exhibits no affinity for lysophosphatidic acid receptor 1 (LPA1) at concentrations up to 10 µM. Inhibits LPA r... 10mg 3404
TOCRIS BIOSCIENCE		 More Info
AT 56 Synthase/Synthetase Inhibitor 10 mg 3531/10
R&D SYSTEMS, INC.		 More Info
AT 56 Synthase/Synthetase Inhibitor 50 mg 3531/50
R&D SYSTEMS, INC.		 More Info
AT 56 Orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS) (Ki = 75 µM, IC50 = 95 µM). Inhibits the production of PGD2 from PGH2 in vitro, with no effect on PGE2 or PGF2alpha production. Minimum Purity: > 99% 10mg 3531
TOCRIS BIOSCIENCE		 More Info
AT 56 Orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS) (Ki = 75 µM, IC50 = 95 µM). Inhibits the production of PGD2 from PGH2 in vitro, with no effect on PGE2 or PGF2alpha production. Minimum Purity: > 99% 50mg 3531
TOCRIS BIOSCIENCE		 More Info
A 582941 Selective alpha7 nAChR partial agonist; exhibits high affinity for both rat and human alpha7 receptors (Ki values are 10.8 and 16.7 nM respectively). Displays ~15-fold selectivity for alpha7 over 5-HT3 receptors (Ki = 150 nM for 5-HT3). Minimum Pu... 10mg 4341
TOCRIS BIOSCIENCE		 More Info
A 582941 Selective alpha7 nAChR partial agonist; exhibits high affinity for both rat and human alpha7 receptors (Ki values are 10.8 and 16.7 nM respectively). Displays ~15-fold selectivity for alpha7 over 5-HT3 receptors (Ki = 150 nM for 5-HT3). Minimum Pu... 50mg 4341
TOCRIS BIOSCIENCE		 More Info
AS 605240 PI 3-Kinase Inhibitor 10 mg 3578/10
R&D SYSTEMS, INC.		 More Info
AS 605240 PI 3-Kinase Inhibitor 50 mg 3578/50
R&D SYSTEMS, INC.		 More Info
AS 605240 Potent and selective inhibitor of PI 3-kinase gamma (PI3Kgamma) (IC50 = 8 nM). Displays 30-fold selectivity over PI3Kdelta and PI3Kbeta and 7.5-fold selectivity over PI3Kalpha. Suppresses the progression of joint inflammation and damage in both ly... 10mg 3578
TOCRIS BIOSCIENCE		 More Info
AS 605240 Potent and selective inhibitor of PI 3-kinase gamma (PI3Kgamma) (IC50 = 8 nM). Displays 30-fold selectivity over PI3Kdelta and PI3Kbeta and 7.5-fold selectivity over PI3Kalpha. Suppresses the progression of joint inflammation and damage in both ly... 50mg 3578
TOCRIS BIOSCIENCE		 More Info
A 740003 P2X Receptor Antagonist 10 mg 3701/10
R&D SYSTEMS, INC.		 More Info
A 740003 P2X Receptor Antagonist 50 mg 3701/50
R&D SYSTEMS, INC.		 More Info
A 740003 Potent, selective and competitive P2X7 receptor antagonist (IC50 values are 18 and 40 nM for rat and human receptors respectively). Displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100 µM. Reduces nocicep... 10mg 3701
TOCRIS BIOSCIENCE		 More Info
A 740003 Potent, selective and competitive P2X7 receptor antagonist (IC50 values are 18 and 40 nM for rat and human receptors respectively). Displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100 µM. Reduces nocicep... 50mg 3701
TOCRIS BIOSCIENCE		 More Info
A 769662 AMPK Activator 10 mg 3336/10
R&D SYSTEMS, INC.		 More Info
A 769662 AMPK Activator 50 mg 3336/50
R&D SYSTEMS, INC.		 More Info
A 769662 Potent, reversible AMP-activated protein kinase (AMPK) activator (EC50 = 0.8 µM) that displays selectivity towards beta1 subunit-containing heterotrimers. Inhibits fatty acid synthesis (IC50 = 3.2 µM) and decreases plasma glucose and t... 10mg 3336
TOCRIS BIOSCIENCE		 More Info
A 769662 Potent, reversible AMP-activated protein kinase (AMPK) activator (EC50 = 0.8 µM) that displays selectivity towards beta1 subunit-containing heterotrimers. Inhibits fatty acid synthesis (IC50 = 3.2 µM) and decreases plasma glucose and t... 50mg 3336
TOCRIS BIOSCIENCE		 More Info
A 803467 n/a 10 mg 2976/10
R&D SYSTEMS, INC.		 More Info
A 803467 n/a 50 mg 2976/50
R&D SYSTEMS, INC.		 More Info
A 803467 Selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively). Shows no significant activity against TRPV1, P2X2/3, CaV2.2 and KCNQ2/3 channels. Anti... 10mg 2976
TOCRIS BIOSCIENCE		 More Info
A 803467 Selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively). Shows no significant activity against TRPV1, P2X2/3, CaV2.2 and KCNQ2/3 channels. Anti... 50mg 2976
TOCRIS BIOSCIENCE		 More Info
A 80426 Adrenergic alpha-2 Receptor Antagonist 10 mg 2341/10
R&D SYSTEMS, INC.		 More Info
A 80426 Adrenergic alpha-2 Receptor Antagonist 50 mg 2341/50
R&D SYSTEMS, INC.		 More Info
A 83-01 A selective inhibitor of TGF-beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-beta-induced epithe... 1 mg 1725-1
BIOVISION, INC.		 More Info
A 83-01 TGF-beta Receptor Inhibitor 10 mg 2939/10
R&D SYSTEMS, INC.		 More Info
A 83-01 TGF-beta Receptor Inhibitor 50 mg 2939/50
R&D SYSTEMS, INC.		 More Info
A 83-01 Selective inhibitor of TGF-beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-beta-induced epitheli... 10mg 2939
TOCRIS BIOSCIENCE		 More Info
A 83-01 Selective inhibitor of TGF-beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-beta-induced epitheli... 50mg 2939
TOCRIS BIOSCIENCE		 More Info
A 839977 P2X Receptor Antagonist 10 mg 4232/10
R&D SYSTEMS, INC.		 More Info
A 839977 P2X Receptor Antagonist 50 mg 4232/50
R&D SYSTEMS, INC.		 More Info
A 839977 Potent P2X7 antagonist; blocks BzATP-evoked calcium influx at recombinant human, rat and mouse P2X7 receptors (IC50 values are 20, 42 and 150 nM respectively). Displays antinociceptive effects in rat and mice models of inflammatory pain. CNS penet... 10mg 4232
TOCRIS BIOSCIENCE		 More Info
A 839977 Potent P2X7 antagonist; blocks BzATP-evoked calcium influx at recombinant human, rat and mouse P2X7 receptors (IC50 values are 20, 42 and 150 nM respectively). Displays antinociceptive effects in rat and mice models of inflammatory pain. CNS penet... 50mg 4232
TOCRIS BIOSCIENCE		 More Info
A 841720 Group I mGluR Antagonist 10 mg 3060/10
R&D SYSTEMS, INC.		 More Info
A 841720 Group I mGluR Antagonist 50 mg 3060/50
R&D SYSTEMS, INC.		 More Info
A 841720 Potent, non-competitive mGlu1 receptor antagonist that displays 34-fold selectivity over mGlu5 (IC50 values are 10 and 342 nM respectively). Displays no significant activity at a range of other GPCRs, ion channels and transporters. Exhibits analge... 10mg 3060
TOCRIS BIOSCIENCE		 More Info
A 841720 Potent, non-competitive mGlu1 receptor antagonist that displays 34-fold selectivity over mGlu5 (IC50 values are 10 and 342 nM respectively). Displays no significant activity at a range of other GPCRs, ion channels and transporters. Exhibits analge... 50mg 3060
TOCRIS BIOSCIENCE		 More Info
A 887826 n/a 10 mg 4249/10
R&D SYSTEMS, INC.		 More Info
A 887826 n/a 50 mg 4249/50
R&D SYSTEMS, INC.		 More Info
A 887826 Potent voltage-dependent NaV1.8 channel blocker (IC50 = 11 nM in recombinant human NaV1.8 channels). Reduces tactile allodynia in neuropathic rat models. 3- and 28-fold more potent at NaV1.8 channels compared to NaV1.2 and NaV1.7 channels respecti... 10mg 4249
TOCRIS BIOSCIENCE		 More Info
A 887826 Potent voltage-dependent NaV1.8 channel blocker (IC50 = 11 nM in recombinant human NaV1.8 channels). Reduces tactile allodynia in neuropathic rat models. 3- and 28-fold more potent at NaV1.8 channels compared to NaV1.2 and NaV1.7 channels respecti... 50mg 4249
TOCRIS BIOSCIENCE		 More Info
92.1.7 n/a n/a n/a VIRCELL S.L. More Info
A 922500 Acyltransferase Inhibitor 10 mg 3587/10
R&D SYSTEMS, INC.		 More Info
A 922500 Diacylglycerol acyltransferase 1 (DGAT-1) inhibitor (IC50 values are 7 and 24 nM at human and mouse DGAT-1 respectively) that is devoid of activity at DGAT-2, ACAT1 or ACAT2. Induces significant weight loss without altering food intake, and decrea... 10mg 3587
TOCRIS BIOSCIENCE		 More Info
A 987306 Histamine H4 Receptor Antagonist 10 mg 3640/10
R&D SYSTEMS, INC.		 More Info
A 987306 Histamine H4 Receptor Antagonist 50 mg 3640/50
R&D SYSTEMS, INC.		 More Info
A 987306 Potent histamine H4 receptor antagonist (pKi values are 8.24 and 8.47 in human and rat H4 receptors respectively). Displays 162-fold, 620-fold, and > 1600-fold selectivity over human H3, H1 and H2 receptors. Blocks zymosan-induced neutrophil reflu... 10mg 3640
TOCRIS BIOSCIENCE		 More Info
A 987306 Potent histamine H4 receptor antagonist (pKi values are 8.24 and 8.47 in human and rat H4 receptors respectively). Displays 162-fold, 620-fold, and > 1600-fold selectivity over human H3, H1 and H2 receptors. Blocks zymosan-induced neutrophil reflu... 50mg 3640
TOCRIS BIOSCIENCE		 More Info
A2.01 n/a n/a n/a
NIH AIDS RESEARCH & REFERENCE REAGENT PROGRAM		 More Info
A3.01 n/a n/a n/a
NIH AIDS RESEARCH & REFERENCE REAGENT PROGRAM		 More Info
A549 n/a n/a n/a VIRCELL S.L. More Info
A-769662 A-769662 Purity is greater than 99%. 10 mg orb60992
BIORBYT LTD.		 More Info
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