Anti-Acrosin Monoclonal Antibody from GENETEX INC.
| Antigenic Specificity | Acrosin |
|---|---|
| Clone | ACR-2 |
| Host Species | Mouse |
| Reactive Species | cross-reacts with pig. does not cross-react with cow, dog or human. not yet tested in other species. |
| Isotype | IgG1 |
| Format | purity: >95% by SDS-PAGE |
| Size | 100 ug, 1 mg/ml |
| Applications | ICC, WB |
| Description | Specificity: The antibody ACR 2 reacts with various forms of porcine acrosin (55, 53, 45 and 35 kDa) in the acrosome of undamaged spermatozoa. Immunogen: Acid extracts of boar spermatozoa were subjected to hydrophobic chromatography and the pooled fraction with reactivity to N-alpha benzoylarginine-4-nitroanilide was used for immunization.. Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids. |
| Catalog # | GTX21900 |
| Price | 295 |
| Other Names | n/a |
| Supplier Data Page | Anti-Acrosin from GENETEX INC. |
GENETEX INC.
14785 Omicron Dr., Suite101
San Antonio TX 78245
Phone: 210-677-8529
Phone: 877-436-3839
Fax: 210-677-8843
Website: http://www.genetex.com
Linscott's Directory disclaims responsibility for the accuracy of any information on this site. Pricing is approximate list price, and actual
prices may vary.