AACOCF3 from CALBIOCHEM/EMD BIOSCIENCES
| Name | AACOCF3 |
|---|---|
| Description | A cell-permeable trifluoromethyl ketone analog of arachidonic acid. Potent and selective slow-binding inhibitor of cytosolic (85 kDa) phospholipase A2 (cPLA2; ~20 µM). Specific inhibition of cPLA2 activity by AACOCF3 partially inhibits TNF-induced apoptosis without inhibition of caspase activity. Causes a significant diminution in thromboxane B2 production in thrombin-stimulated platelets. Also inhibits platelet aggregation in response to collagen and arachidonic acid. |
| Size | n/a |
| Applications | n/a |
| Catalog # | 100109 |
| Price | n/a |
| Other Names | Arachidonyltrifluoromethyl Ketone |
| Supplier Data Page | AACOCF3 from CALBIOCHEM/EMD BIOSCIENCES |
CALBIOCHEM/EMD BIOSCIENCES
an Affiliate of Merck KGaA, Darmstadt, Germany
P.O. Box 12087
La Jolla CA 92039-2087
Phone: 858-450-9600
Phone: 800-854-3417
Fax: 858-453-3552
Website: http://www.calbiochem.com
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