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Linscott's Directory of Immunological & Biological Reagents
BIOVISION, INC.
 (http://www.biovision.com)

BIOVISION, INC.

155 S. Milpitas Boulevard

Milpitas CA 95035

Phone: 408-493-1800

Phone: 800-891-9699

Fax: 408-493-1801

Email: support@biovision.com

Website: http://www.biovision.com

 
ABT-869 from BIOVISION, INC.

ABT-869 from BIOVISION, INC.

Name ABT-869
Description ABT-869 is multi-targeted inhibitor of all members of the VEGF and PDGF receptor families (e.g., KDR, IC50 value of 4 nM), but has much less activity (IC50 values >1 µM) against unrelated receptor tyrosine kinases, soluble tyrosine kinases or serine/threonine kinases. The kinase inhibition profile of ABT-869 is evident in cellular assays of RTK phosphorylation (IC50 values of 2, 4 and 7 nM for PDGFRbeta, KDR and CSF-1R, respectively) and VEGF-stimulated proliferation (0.2 nM IC50 for human endothelial cells).
Size 5 mg
Applications n/a
Catalog # 1615-5
Price $895
Other Names Linifanib
Supplier Data Page ABT-869 from BIOVISION, INC.
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