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ABT-869 from BIOVISION, INC.
ABT-869 from BIOVISION, INC.
| Name |
ABT-869 |
| Description |
ABT-869 is multi-targeted inhibitor of all members of the VEGF and PDGF receptor families (e.g., KDR, IC50 value of 4 nM), but has much less activity (IC50 values >1 µM) against unrelated receptor tyrosine kinases, soluble tyrosine kinases or serine/threonine kinases. The kinase inhibition profile of ABT-869 is evident in cellular assays of RTK phosphorylation (IC50 values of 2, 4 and 7 nM for PDGFRbeta, KDR and CSF-1R, respectively) and VEGF-stimulated proliferation (0.2 nM IC50 for human endothelial cells). |
| Size |
5 mg |
| Applications |
n/a |
| Catalog # |
1615-5 |
| Price |
$895 |
| Other Names |
Linifanib |
| Supplier Data Page |
ABT-869 from BIOVISION, INC. |
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