IDH305 from CAYMAN CHEMICAL COMPANY
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| Product Name | IDH305 |
| Description | A potent and selective inhibitor of mutant IDH1 (IC50s = 27, 28, and 6,140 nM for recombinant IDH1R132H, IDH1R132C, and wild-type IDH1, respectively); reduces 2-HG production and inhibits growth of MCF-10A-IDH1R132H/+ cells in a concentration-dependent manner; reduces concentration of tumor 2-HG in an HCT116-IDH1R132H/+ mouse xenograft model (200 mg/kg); suppresses 2-HG production and reduces tumor progression in an HMEX2838-IDH1R132C patient-derived melanoma mouse xenograft model (300 mg/kg), |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 2HG IDH-305 MCF10AIDH1 MCF10A IDH-2 HCT-116 |
| Gene, Accession, CAS # | CAS: 1628805-46-8 |
| Catalog # | 24107-10 |
| Price | $713.00 |
| Order / More Info | IDH305 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY