Longdaysin from CAYMAN CHEMICAL COMPANY
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| Product Name | Longdaysin |
| Description | A CK1δ and CK1α inhibitor (IC50 = 12 µM for both); inhibits Cdk2, Cdk7, MAPK, and MAP3K (IC50s = 13, 32, 59, and 92 µM, respectively); increases the circadian period of U2OS cells by one and five hours at 0.39 and 3.4 µM, respectively; inhibits Wnt-signaling induced by Wnt3A-containing conditioned medium in HEK293 cells and reduces levels of active β-catenin in HEK293 cells expressing CK1δ or CK1ε; reduces colony formation, as well as cell migration and invasion, by Hs 578T and MDA-MB-231 cells at 10 and 25 µM; reduces tumor volume in an MDA-MB-231 mouse xenograft model at 5 mg/kg,, |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | CK 1δ 1α 1ε Cdk 2 7 MAP 3K U2 OS Wnt 3A HEK 293 βcatenin Hs578T MDAMB-231 MDAMB231 MDA-MB231 xeno graft |
| Gene, Accession, CAS # | CAS: 1353867-91-0 |
| Catalog # | 36706-25 |
| Price | $402.00 |
| Order / More Info | Longdaysin from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY