β-Secretase Inhibitor IV from CAYMAN CHEMICAL COMPANY
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| Product Name | β-Secretase Inhibitor IV |
| Description | An inhibitor of BACE1 and 2 (IC50s = 15 and 230 nM for human BACE1 and 2, respectively); has >500-fold selectivity for BACE1 and 2 over the aspartyl proteases renin and cathepsin D; inhibits secretion of APP (IC50 = 29 nM) in HEK293T cells transfected with a truncated human APP; inhibits formation of the Aβ peptides Aβ38, Aβ40, and Aβ42 in primary chick neurons (IC50s = 3.7, 4.7, and 4.8 nM, respectively) |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Axon 1125 Axon1125 38 40 42 BACE 1 BACE2 |
| Gene, Accession, CAS # | CAS: 797035-11-1 |
| Catalog # | 23388-5 |
| Price | $993.00 |
| Order / More Info | β-Secretase Inhibitor IV from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY