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Product Name | TGN 020 |
Description | An AQP4 inhibitor (IC50 = 3.1 µM in X. laevis oocytes transfected with AQP4); reduces brain edema and cortical infarction size in a mouse model of MCAO-induced transient focal cerebral ischemia at 200 mg/kg; reduces BALF IL-1α, IL-1β, IL-6, TNF-α, IL-23, and IL-17A levels and neutrophil infiltration, as well as increases survival, in a mouse model of LPS-induced acute lung injury at 200 mg/kg every 6 hours |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | TGN020 pyridine-carboxamide N-(1,3,4-Thiadiazolyl)-m-nicotinamide Nicotinamido AQP-4 Xenopus IL1α IL1β IL6 TNFα IL23 IL17A Lipopolysaccharide |
Gene, Accession, CAS # | CAS: 51987-99-6 |
Catalog # | 30955-25 |
Price | $200.00 |
Order / More Info | TGN 020 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |