GS-39783 from CAYMAN CHEMICAL COMPANY
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| Product Name | GS-39783 |
| Description | A positive allosteric modulator of GABAB receptors; potentiates GABA-stimulated [35S]GTPγS binding to recombinant human GABAB receptors and rat cortical membranes (EC50s = 2.1 and 3.1 µM, respectively); amplifies GABAB receptor-mediated transient calcium signaling in HEK293 cells expressing human receptors (EC50 = 2.4 µM); suppresses alcohol self-administration in Indiana alcohol-preferring, Sardinian alcohol-preferring, and Alko Alcohol rats from 25-100 mg/kg; reduces amphetamine- or MK-801-induced hyperactivity in rats and the number of DOI-induced head twitches in mice; reduces the incidence of sound-induced tonic convulsions in juvenile mice (ED50 = 55.38 mg/kg) |
| Size | 50 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | GS39783 GABA-B GTPγ-S GTP-γS HEK-293 MK801 anti-psychotic |
| Gene, Accession, CAS # | CAS: 39069-52-8 |
| Catalog # | 29482-50 |
| Price | $535.00 |
| Order / More Info | GS-39783 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
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http://www.caymanchem.com
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