Setmelanotide (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY
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| Product Name | Setmelanotide (trifluoroacetate salt) |
| Description | A peptide agonist of MC4R; increases cAMP production in CHO-K1 cells expressing MC4R, MC1R, MC3R, and MC5R (EC50s = 0.27, 5.8, 5.3, and 1,600 nM, respectively, for the human receptors) but not in cells expressing MC2R (EC50 = >10 µM); inhibits food intake in MC3R, but not MC4R, knockout mice at 6.4 µmol/animal; reduces food intake and hepatosteatosis, induces weight loss, and decreases serum insulin, glucose, and leptin levels in a mouse model of diet-induced obesity at 300 nmol/kg per day |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | BIM-22493|N-acetyl-RCAHFRWC-NH2|RM-493 |
| Gene, Accession, CAS # | n/a |
| Catalog # | 35564-25 |
| Price | $249.00 |
| Order / More Info | Setmelanotide (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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