ZL0420 from CAYMAN CHEMICAL COMPANY
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| Product Name | ZL0420 |
| Description | A BRD4 inhibitor; inhibits BD1 and BD2 in BRD4 (IC50s = 27 and 32 nM, respectively); selective for BD1 and BD2 in BRD4 over BD1 in BRD2, BRD3, and BRDT (IC50s = 803, 2,275, and 3,183 nM, respectively) and BD2 (IC50s = 1,736, 2,193, and 2,781 nM, respectively), as well as the bromodomain in CBP (IC50 = >10,000 nM); inhibits neutrophil infiltration around small- and medium-sized airways and reduces cytokine expression in lung tissue in a poly(I:C)-induced mouse model of acute airway inflammation at 10 mg/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | ZL-0420 BD-1 2 BRD-4 ISG-54 56 IL8 Gro-β TLR-3 |
| Gene, Accession, CAS # | CAS: 2229039-45-4 |
| Catalog # | 30741-5 |
| Price | $121.00 |
| Order / More Info | ZL0420 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY