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Product Name | ZL0420 |
Description | A BRD4 inhibitor; inhibits BD1 and BD2 in BRD4 (IC50s = 27 and 32 nM, respectively); selective for BD1 and BD2 in BRD4 over BD1 in BRD2, BRD3, and BRDT (IC50s = 803, 2,275, and 3,183 nM, respectively) and BD2 (IC50s = 1,736, 2,193, and 2,781 nM, respectively), as well as the bromodomain in CBP (IC50 = >10,000 nM); inhibits neutrophil infiltration around small- and medium-sized airways and reduces cytokine expression in lung tissue in a poly(I:C)-induced mouse model of acute airway inflammation at 10 mg/kg |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | ZL-0420 BD-1 2 BRD-4 ISG-54 56 IL8 Gro-β TLR-3 |
Gene, Accession, CAS # | CAS: 2229039-45-4 |
Catalog # | 30741-10 |
Price | $218.00 |
Order / More Info | ZL0420 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |