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Product Name | Lonafarnib |
Description | A farnesyltransferase inhibitor that blocks the post-translational lipid modification of oncogenic Ras isoforms H-Ras, N-Ras, and K-Ras (IC50s = 1.9, 2.8, and 5.2 nM, respectively) and Rheb (IC50 = 10-100 nM); demonstrates potent dose-dependent oral activity in an array of human tumor xenograft models including tumors originating from colon, lung, pancreas, prostate, and urinary bladder |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Sarasar|SCH 66336 |
Gene, Accession, CAS # | CAS: 193275-84-2 |
Catalog # | 11746-10 |
Price | $143.00 |
Order / More Info | Lonafarnib from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |