TH-302 from CAYMAN CHEMICAL COMPANY
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| Product Name | TH-302 |
| Description | A hypoxia-activated prodrug and DNA alkylating agent with anticancer activity; selectively cytotoxic to H460 human NSCLC cells grown under hypoxic over normoxic conditions (IC50s = 0.019 and 5.1 µM, respectively); reduces survival of H460 and HT-29 cells in a clonogenic assay (IC50s = 0.2 and 0.2 µM, respectively); inhibits primary tumor growth by 41% in an MIA PaCa-2-RFP mouse orthotopic xenograft model at 33 mg/kg per day; inhibits tumor growth in the Calu-6 NSCLC, H82 small cell lung, A375 melanoma, PC-3 prostate, and BxPC-3 pancreatic cancer mouse xenograft models at 50 mg/kg |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Evofosfamide |
| Gene, Accession, CAS # | CAS: 918633-87-1 |
| Catalog # | 22195-1 |
| Price | $40.00 |
| Order / More Info | TH-302 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY