TB 21007 from CAYMAN CHEMICAL COMPANY
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| Product Name | TB 21007 |
| Description | An inverse agonist of α5β3γ2 subunit-containing GABAA receptors (Ki = 1.6 nM); selectively inhibits α5β3γ2 subunit-containing GABAA receptors over α1-4 and α6 subunit-containing GABAA receptors that also contain β3 and γ2 subunits (Kis = 20, 16, 20, 106, and 1,800 nM, respectively); reduces the latency to find the hidden platform in a matching-to-place variant of the Morris water maze, indicating enhanced spatial memory, in rats at 0.3 mg/kg; reduces reserpine-induced paw tactile allodynia in a rat model of fibromyalgia-like pain at 1.5, 15, and 150 nmol intrathecally |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | TB21007 α5 β3 β 3 γ2 γ 2 GABA A α 1 5 6 |
| Gene, Accession, CAS # | CAS: 207306-50-1 |
| Catalog # | 27674-10 |
| Price | $195.00 |
| Order / More Info | TB 21007 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
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