TG6-10-1 from CAYMAN CHEMICAL COMPANY
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| Product Name | TG6-10-1 |
| Description | A potent EP2 receptor antagonist (Kb = 17.8 nM in C6 glioma cells overexpressing human EP2); 300-, 25-, and 10-fold selective for EP2 over other human EP3-4, FP and TP, and DP1 receptors, respectively; selective for EP2 over a panel of 40 enzymes, ion channels, receptors, and neurotransmitter transporters (IC50s >10 µM); increases survival, decreases weight loss, prevents induction of IL-1β, IL-6, TNF-α, and MCP-1/CCL2 mRNA, and inhibits neuronal cell death in the hippocampus in mouse and rat models of status epilepticus induced by pilocarpine and diisopropyl fluorophosphate, respectively |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | TG610-1 TG6-101 TG6101 EP-2 3 4 DP-2 IL1β IL6 TNFα MCP1 CCL-2 EP3 EP4 DP-1 IL1B TNFa |
| Gene, Accession, CAS # | CAS: 1415716-58-3 |
| Catalog # | 23444-10 |
| Price | $231.00 |
| Order / More Info | TG6-10-1 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY