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Product Name | Pixantrone (maleate) |
Description | A DNA topoisomerase II inhibitor; induces SV40 DNA cleavage in the presence of mouse topoisomerase II; induces DNA single-strand breaks in NCI H187 cells; is cytotoxic to L1210 cells as well as doxorubicin-sensitive and -resistant LoVo cells (IC50 = 0.01, 0.24, and 7.2 µg/ml, respectively); decreases disease severity in a rat model of T. californica AChR immunization-induced myasthenia gravis at 8.12 mg/kg once per week for six weeks |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | BBR 2778 |
Gene, Accession, CAS # | CAS: 144675-97-8 |
Catalog # | 20055-1 |
Price | $32 |
Order / More Info | Pixantrone (maleate) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |