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Product Name | rac-Benpyrine |
Description | An inhibitor of the TNF-α-TNFR1 protein-protein interaction (IC50 = 0.109 µM); reduces TNF-α induced cytotoxicity in L-929 fibroblasts at 10 µM; prevents nuclear translocation of NF-κB in RAW 264.7 macrophages; improves survival in a mouse model of LPS-induced endotoxemia and decreases disease severity in mouse models of collagen-induced arthritis and imiquimod-induced psoriasis at 25 mg/kg |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | TNFα TNFR-1 L929 NFκB Lipopolysaccharide |
Gene, Accession, CAS # | CAS: 1333714-43-4 |
Catalog # | 36680-1 |
Price | $51 |
Order / More Info | rac-Benpyrine from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |