RECTAS from CAYMAN CHEMICAL COMPANY
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| Product Name | RECTAS |
| Description | A pre-mRNA splicing modulator; corrects aberrant splicing in a SPREADD using HeLa cells expressing IKBKAP with an IVS20 + 6T>C point mutation; restores the modification of cytoplasmic tRNAs with uridine in the wobble position in primary human fibroblasts from patients with FD to the same level as in primary human fibroblasts from carriers of the FD mutation at 2 µM; increases the levels of correctly spliced PARK7 mRNA in neural precursor cells differentiated from fibroblasts of patients with the homozygous PARK7 c.192G>C exonic splicing mutation in combination with phenylbutyric acid; intratumoral administration decreases tumor volume and increases survival and the number of tumor-infiltrating CD8+ T cells in an MC-38 murine colon carcinoma model |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | NSC 45794|Rectifier of Aberrant Splicing |
| Gene, Accession, CAS # | CAS: 101862-47-9 |
| Catalog # | 38322-10 |
| Price | $165 |
| Order / More Info | RECTAS from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY