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Product Name | Losartan Carboxaldehyde |
Description | An active metabolite of losartan; inhibits arachidonic acid-induced platelet aggregation in isolated human platelet-rich plasma at 10 pM; a PPARγ agonist (EC50 = 17.1 µM in COS-7 cells expressing human PPARγ using a reporter assay); increases lipid accumulation in 3T3-L1 adipocytes at 10 µM; decreases superoxide production by NOX in isolated human PBMCs in a concentration-dependent manner; inhibits LPS-induced increases in COX2 mRNA expression and LPS- or angiotensin II-induced increases in supernatant PGF2α levels in HUVECs at 10 µM |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | DuP-167|E3179|EXP3179 |
Gene, Accession, CAS # | CAS: 114798-36-6 |
Catalog # | 18855-10 |
Price | $249.00 |
Order / More Info | Losartan Carboxaldehyde from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |