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Product Name | BI-9627 |
Description | An NHE1 inhibitor (IC50s = 6 and 31 nM in pHi and human platelet swelling assays, respectively); greater than 30-fold selective for NHE1 over NHE2 and is inactive at NHE3 up to 16 µM in a pHi assay; inhibits phenylephrine-induced hypertrophy in neonatal rat cardiomyocytes; increases recovery of left ventricular developed pressure and inhibits increases in LVEDP in a Langendorff isolated perfused rat heart model of ischemia-reperfusion injury at 100 nM; attenuates decreases in left ventricular end-systolic pressure and increases in LVEDP in coronary artery-ligated rats at 45 and 150 ppm in the diet |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1422252-46-7 BI9627 NHE 1 2 3 pH i A187160 A 187160 BIX |
Gene, Accession, CAS # | CAS: 1204329-34-9 |
Catalog # | 27640-10 |
Price | $195.00 |
Order / More Info | BI-9627 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |