Edit |   |
---|---|
Product Name | BIBP3226 |
Description | A nonpeptide antagonist of NPY Y1 (Ki = 1.1 nM); selective for Y1 over Y2, Y4, and Y5 receptors (Kis = >1,000 nM for all); binds to NPFF1 and NPFF2 (Kis = 108 and 79 nM, respectively) and reverses NPFF-induced inhibition of forskolin-induced cyclic AMP accumulation in CHO cells expressing human NPFF2; inhibits NPY-induced perfusion pressure increases in isolated rat kidney (IC50s = 26 nM); inhibits NPY-induced increases in blood pressure in pithed rats (ED50 = 0.11 mg/kg); inhibits NPFF-induced hypothermia in mice at 5 nmol, i.c.v. |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | BIBP-3226 non-peptide NP FF1 FF2 |
Gene, Accession, CAS # | CAS: 159013-54-4 |
Catalog # | 33210-10 |
Price | $333.00 |
Order / More Info | BIBP3226 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |