BIBP3226 from CAYMAN CHEMICAL COMPANY
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| Product Name | BIBP3226 |
| Description | A nonpeptide antagonist of NPY Y1 (Ki = 1.1 nM); selective for Y1 over Y2, Y4, and Y5 receptors (Kis = >1,000 nM for all); binds to NPFF1 and NPFF2 (Kis = 108 and 79 nM, respectively) and reverses NPFF-induced inhibition of forskolin-induced cyclic AMP accumulation in CHO cells expressing human NPFF2; inhibits NPY-induced perfusion pressure increases in isolated rat kidney (IC50s = 26 nM); inhibits NPY-induced increases in blood pressure in pithed rats (ED50 = 0.11 mg/kg); inhibits NPFF-induced hypothermia in mice at 5 nmol, i.c.v. |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | BIBP-3226 non-peptide NP FF1 FF2 |
| Gene, Accession, CAS # | CAS: 159013-54-4 |
| Catalog # | 33210-25 |
| Price | $711.00 |
| Order / More Info | BIBP3226 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
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