Xaliproden (hydrochloride) from CAYMAN CHEMICAL COMPANY

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Product NameXaliproden (hydrochloride)
DescriptionA 5-HT1A agonist (IC50 = 4.3 nM in a radioligand binding assay); selective for 5-HT1A over 5-HT2 and α1-adrenergic receptors (IC50s = 697 and 630 nM, respectively), as well as a panel of 13 additional neurotransmitter receptors and ion channels (IC50s = ≥10 µM for all) but also binds σ receptors (IC50 = 73 nM); increases NGF-induced neurite outgrowth and α-actinin levels in PC12 cells at 250 nM; decreases hippocampal neuronal damage and reduces impairments in sensorimotor function in rat models of transient global ischemia induced by 4-VO and sciatic nerve crush injury, respectively, at 10 mg/kg per day; inhibits CNS mononuclear cell infiltration and increases in cerebrospinal fluid IgG levels in a rat model of EAE induced by myelin basic protein at 10 mg/kg per day
Size50 mg
Concentrationn/a
Applicationsn/a
Other NamesSR 57746A
Gene, Accession, CAS #CAS: 90494-79-4
Catalog #31468-50
Price$517.00
Order / More InfoXaliproden (hydrochloride) from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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