Cortistatin-14 (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY

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Product NameCortistatin-14 (trifluoroacetate salt)
DescriptionAn endogenous neuropeptide agonist of SST1-SST5 (IC50s = 0.5-18.2 nM for human receptors expressed in CCL39 cells); [KC1] competitively inhibits hexarelin binding to GHS-R in pituitary membranes (Ki = 0.54 µM); activates the human MrgX2 receptor expressed in HEK293 cells (EC50 = 1.3 µM); completely inhibits TRH, and partially inhibits VIP, stimulation of cAMP production in GH4 cells (0.01-1 µM); dose-dependently impairs memory retention in mice when delivered after foot shock avoidance training (0.05-5 µg, i.c.v.); dose-dependently reduces growth hormone secretion in rats with a reduction of over 80% at all concentrations after 10 minutes (40-320 µg/kg s.c.)
Size500 µg
Concentrationn/a
Applicationsn/a
Other Names186901-48-4 193829-96-8 937031-00-0 CCL 39 SST GHSR GH-4 Mrg-X2
Gene, Accession, CAS #n/a
Catalog #25074-500
Price$110.00
Order / More InfoCortistatin-14 (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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