Muraglitazar from CAYMAN CHEMICAL COMPANY
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| Product Name | Muraglitazar |
| Description | A dual agonist of PPARα and PPARγ (EC50s = 0.32 and 0.11 µM, respectively); selective for PPARα/γ over other nuclear receptors, including PPARδ, RXRα, RARs, ERα/β, AR, and PR; reduces the size of lipid droplets in oleic acid-treated HepaRG human hepatocytes at 50 µM; reduces plasma levels of glucose, triglycerides, free fatty acids, and insulin by 54, 33, 62, and 48%, respectively, in db/db mice at 10 mg/kg per day; reduces plasma levels of glucose, triglycerides, and cholesterol in diet-induced obese mice at 10 mg/kg per day; inhibits LPS-induced increases in NO production and IL-6, TNF-α, and iNOS protein levels in J774 murine macrophages; inhibits carrageenan-induced paw edema in mice at 12.5-50 mg/kg |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | BMS-298585 |
| Gene, Accession, CAS # | CAS: 331741-94-7 |
| Catalog # | 10007853-1 |
| Price | $341.00 |
| Order / More Info | Muraglitazar from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY