C-02 from CAYMAN CHEMICAL COMPANY
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| Product Name | C-02 |
| Description | A PROTAC that drives hexokinase 2 degradation; induces degradation of hexokinase 2 in 786-O and PANC-1 cells at 20 µM; cytotoxic to 786-O, 4T1, PANC-1, HGC-27, and MCF-7 cancer cells (IC50s = 34.07, 5.08, 31.53, 6.11, and 21.65 µM, respectively); reduces ECAR and OCR in 4T1 cells at 20 µM; reduces tumor volume and induces intratumoral cytokine accumulation and pyroptosis in a 4T1 murine mammary carcinoma model at 50 mg/kg,, |
| Size | 500 µg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | C02 hexo kinase 786O PANC1 4T 1 HGC27 MCF7 |
| Gene, Accession, CAS # | n/a |
| Catalog # | 39384-500 |
| Price | $27.00 |
| Order / More Info | C-02 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY