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Product Name | Carisbamate |
Description | An antiepileptic agent; dose-dependently reduces spike and wave discharges in the frontoparietal cortex in a rat model of absence seizures at doses of 10-60 mg/kg; increases latency to the first running episode in the Wistar audiogenic sensitive rat model of convulsive seizures; reduces motor seizure frequency in a rat model of spontaneous seizures in a dose-dependent manner; blocks Nav1.2 channels (IC50 = 68 µM for rat channels); inhibits repetitive firing of action potentials in rat hippocampal neurons in a dose-dependent manner; reduces T-type Ca2+ currents in HEK cells transfected with human recombinant Cav3.1 channels at a concentration of 300 µM |
Size | 500 µg |
Concentration | n/a |
Applications | n/a |
Other Names | JNJ-10234094|RWJ 333369 |
Gene, Accession, CAS # | CAS: 194085-75-1 |
Catalog # | 23514-500 |
Price | $121.00 |
Order / More Info | Carisbamate from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |