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Product Name | LY2228820 (mesylate) |
Description | A potent inhibitor of p38α MAP kinase (IC50 = 7 nM for human recombinant p38α); inhibits LPS-induced TNF-α production in murine peritoneal macrophages and reduces phosphorylation of MK2 in RAW 264.7 cells (IC50s = 5.2 and 34.3 nM, respectively); inhibits TNF-α production in LPS-treated mice and reduces paw swelling and cartilage destruction in a rat model of chronic inflammation (TMED50s = <1, 1.5, and 1.5 mg/kg, respectively) |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | LSN2322600 |
Gene, Accession, CAS # | CAS: 862507-23-1 |
Catalog # | 23259-10 |
Price | $275.00 |
Order / More Info | LY2228820 (mesylate) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |