Edit |   |
---|---|
Product Name | R-568 |
Description | A calcimimetic and positive allosteric modulator of CaSR; potentiates extracellular calcium-induced increases in intracellular calcium release and inhibits the secretion of PTH (IC50 = 27 nM) in bovine parathyroid cells; decreases PTH and plasma calcium levels in rats (ED50s = 1.1 and 10.4 mg/kg, respectively); suppresses parathyroid cell proliferation in a rat model of chronic renal insufficiency at 15 mg/kg |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | KRN 568|NPS R-568|Tecalcet |
Gene, Accession, CAS # | CAS: 177172-49-5 |
Catalog # | 17415-50 |
Price | $704 |
Order / More Info | R-568 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |