6-OHDA (hydrobromide) from CAYMAN CHEMICAL COMPANY
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| Product Name | 6-OHDA (hydrobromide) |
| Description | A catecholaminergic neurotoxin; has been used to induce dopaminergic lesions and parkinsonian symptoms as a model of Parkinson's disease in rodents; induces locomotor impairment in mice and loss of tyrosine hydroxylase-reactive neurons in mouse brain when administered into the substantia nigra, MFB, or striatum at doses of 9, 6, and 18 µg, respectively; decreases dopamine and norepinephrine levels in rat brain at 200 µg; induces apoptosis in primary rat cortical cells and PC12 rat adrenal cells at 50 µM; activates caspase-3, -8, and -9 in a time-dependent manner and increases the level of intracellular ROS in PC12 cells at 75 µM; induces apoptosis in rat substantia nigra when stereotaxically injected into the right MFB |
| Size | 1 g |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 2,4,5-Trihydroxyphenethylamine|6-hydroxy Dopamine|Oxidopamine |
| Gene, Accession, CAS # | CAS: 636-00-0 |
| Catalog # | 25330-1 |
| Price | $432.00 |
| Order / More Info | 6-OHDA (hydrobromide) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY