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Product Name | Mogrol |
Description | An aglycone with diverse biological activities; inhibits the proliferation and migration of A549, H1299, H1975, and SK-MES-1 lung cancer cells from 10-50 µM; induces AMPK activation and autophagy, as well as apoptosis and cell cycle arrest at the G1 phase in A549 cells at 50 µM; reduces tumor weight and volume in an A549 mouse xenograft model at 10 mg/kg; reduces colonic inflammatory cell infiltration and colonic shortening in a mouse model of DSS-induced ulcerative colitis at 5 mg/kg; improves LPS-induced memory impairments and decreases hippocampal and frontal cortex levels of TNF-α, IL-1β, and IL-6 in LPS-challenged mice |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Siraitia A-549 H-1299 1975 SK-MES1 SKMES1 SKMES-1 TNFα IL1β IL6 |
Gene, Accession, CAS # | CAS: 88930-15-8 |
Catalog # | 39253-50 |
Price | $498.00 |
Order / More Info | Mogrol from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |