MRK-560 from CAYMAN CHEMICAL COMPANY
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| Product Name | MRK-560 |
| Description | A potent inhibitor of γ-secretase (IC50 = 0.65 nM); reduces diethanolamine-soluble Aβ40 levels in APP-YAC transgenic mouse brain from 1-10 mg/kg; reduces brain and cerebrospinal fluid Aβ40 levels in rats (ED50s = 6 and 10 mg/kg, respectively); decreases brain-soluble Aβ40 and Aβ42 levels and recovers hippocampal long-term potentiation in the Tg2576 transgenic mouse model of Alzheimer's disease |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | MRK560 γsecretase amyloidβ APPYAC Aβ 40 42 Tg 2576 |
| Gene, Accession, CAS # | CAS: 677772-84-8 |
| Catalog # | 27599-1 |
| Price | $106.00 |
| Order / More Info | MRK-560 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY