TGR5 Receptor Agonist from CAYMAN CHEMICAL COMPANY
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| Product Name | TGR5 Receptor Agonist |
| Description | An agonist of the bile acid G protein-coupled receptor TGR5 (EC50s = 31.6-158.5 nM in cell-based assays); stimulates cAMP formation in HEK293 cells expressing TGR5 (EC50 = 2.3 pM); increases GLP-1 secretion and decreases glucose levels in the hepatic portal vein in dogs at 1 mg/kg when administered in combination with glucose; inhibits the CYP isozymes CYP2C19 and CYP3A4 (IC50s = 316.2 and 1,259 nM, respectively) |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | TGR-5 CCDC HEK-293 GLP1 P-450 CYP-2C19 3A4 |
| Gene, Accession, CAS # | CAS: 1197300-24-5 |
| Catalog # | 16291-1 |
| Price | $32.00 |
| Order / More Info | TGR5 Receptor Agonist from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY