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Product Name | Dimethyl 2-ketoglutarate |
Description | An esterified form of α-ketoglutarate; increases intracellular levels of α-ketoglutarate and decreases intracellular ATP levels in U2OS human osteosarcoma cells cultured in complete- or nutrient-free media at 5 mM; inhibits autophagy and decreases in intracellular levels of acetyl-CoA in serum- and nutrient-deprived cells; decreases cardiomyocyte hypertrophy in a thoracic aortic constriction-induced mouse model of cardiac pressure overload at 300 mg/kg; reduces serum AST and ALT levels and hepatic fibrosis in a rat model of CCl4-induced liver fibrosis |
Size | 1 g |
Concentration | n/a |
Applications | n/a |
Other Names | 2-KG dimethyl ester|Dimethyl 2-oxoglutarate|Dimethyl α-ketoglutarate |
Gene, Accession, CAS # | CAS: 13192-04-6 |
Catalog # | 28394-1 |
Price | $44.00 |
Order / More Info | Dimethyl 2-ketoglutarate from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |