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Product Name | LY411575 |
Description | A cell-permeable γ-secretase inhibitor (IC50 = 0.14 nM) that has been shown to block Notch activation in vitro at 500 µM; induces apoptosis in Kaposi's sarcoma cells, promotes intestinal goblet cell differentiation in a mouse model of colitis, and promotes neural differentiation of mouse embryonic stem cells |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | γ-secretase .gamma.-secretase gamma-secretase g-secretase γ secretases .gamma. gamma g proteases Notch inhibitors inhibits inhibitions cells proliferation differentiation apoptosis signaling signals Notch LYs 411575 LY-411575 kaposi's kaposi kaposis sarcoma neural stems biology intracellular transduction research |
Gene, Accession, CAS # | CAS: 209984-57-6 |
Catalog # | 16162-5 |
Price | $116.00 |
Order / More Info | LY411575 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |